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product-image-AAA111272_AD10.jpg Application Data (Flow Cytometry analysis of K562 cells stained with TORC1(N-terminus) (red, 1/100 dilution), followed by FITC-conjugated goat anti-mouse IgG. Blue line histogram represents the isotype control, normal mouse IgG.)

Mouse anti-Human TORC1 Monoclonal Antibody | anti-TORC1 antibody

TORC1 (MECT1) Antibody

Gene Names
CRTC1; MECT1; TORC1; TORC-1; WAMTP1
Reactivity
Human
Applications
Immunoprecipitation, Immunocytochemistry, Flow Cytometry, Functional Assay, Western Blot
Purity
Affinity purified
Synonyms
TORC1, Antibody; TORC1 (MECT1) Antibody; KIAA0616; CREB regulated transcription coactivator 1; CREB-regulated transcription coactivator 1; CRTC1; CRTC1_HUMAN; FLJ14027; MECT 1; Mucoepidermoid carcinoma translocated 1; Mucoepidermoid carcinoma translocated protein 1; TORC-1; TORC1; Transducer of CREB protein 1; Transducer of regulated cAMP response element binding protein 1; Transducer of regulated cAMP response element-binding protein (CREB) 1; Transducer of regulated cAMP response element-binding protein 1; WAMTP1; anti-TORC1 antibody
Ordering
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b
Specificity
This antibody detects endogenous levels of TORC1(N-terminus) and does not cross-react with related proteins.
Purity/Purification
Affinity purified
Form/Format
Purified in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%, glycerol
Sequence Length
650
Applicable Applications for anti-TORC1 antibody
IP (Immunoprecipitation), ICC (Immunocytochemistry), FCM/FACS (Flow Cytometry), WB (Western Blot)
Immunogen
Purified recombinant human TORC1(N-terminus) protein fragments expressed in E Coli.
Cellular Localization
Cytoplasm; Nucleus

Application Data

(Flow Cytometry analysis of K562 cells stained with TORC1(N-terminus) (red, 1/100 dilution), followed by FITC-conjugated goat anti-mouse IgG. Blue line histogram represents the isotype control, normal mouse IgG.)

product-image-AAA111272_AD10.jpg Application Data (Flow Cytometry analysis of K562 cells stained with TORC1(N-terminus) (red, 1/100 dilution), followed by FITC-conjugated goat anti-mouse IgG. Blue line histogram represents the isotype control, normal mouse IgG.)

Application Data

(Immunoprecipitation analysis of Hela cell lysate using CRTC1 antibody.)

product-image-AAA111272_AD11.jpg Application Data (Immunoprecipitation analysis of Hela cell lysate using CRTC1 antibody.)

Application Data

(Western blot detection of TORC1(N-terminus) antibody in Hela&Jurkat lysates using TORC1(N-terminus) antibody (1:1000 diluted). Predicted band size: 69KDa Observed band size: 69KDa.)

product-image-AAA111272_AD13.jpg Application Data (Western blot detection of TORC1(N-terminus) antibody in Hela&Jurkat lysates using TORC1(N-terminus) antibody (1:1000 diluted). Predicted band size: 69KDa Observed band size: 69KDa.)

Application Data

(Immunocytochemistry stain of Hela using TORC1 antibody (1:300).)

product-image-AAA111272_AD15.jpg Application Data (Immunocytochemistry stain of Hela using TORC1 antibody (1:300).)
Related Product Information for anti-TORC1 antibody
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 ´Ser-133´ phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses (By similarity)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
69kDa
NCBI Official Full Name
CREB-regulated transcription coactivator 1 isoform 3
NCBI Official Synonym Full Names
CREB regulated transcription coactivator 1
NCBI Official Symbol
CRTC1
NCBI Official Synonym Symbols
MECT1; TORC1; TORC-1; WAMTP1
NCBI Protein Information
CREB-regulated transcription coactivator 1
UniProt Protein Name
CREB-regulated transcription coactivator 1
UniProt Gene Name
CRTC1
UniProt Synonym Gene Names
TORC-1; Transducer of CREB protein 1

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Product Notes

The TORC1 crtc1 (Catalog #AAA111272) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TORC1 (MECT1) Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TORC1 can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), ICC (Immunocytochemistry), FCM/FACS (Flow Cytometry), WB (Western Blot). Researchers should empirically determine the suitability of the TORC1 crtc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TORC1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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