Application Data
(Cell surface staining of THP1 cells. Green represents Isotype control. Red represents Anti-TSLP Receptor (AAA78228). 0.5 µg antibodies were used. Goat anti- mouse PE was used as secondary antibody.)
Mouse anti-Human TSLP Receptor Monoclonal Antibody | anti-CRLF2 antibody
TSLP Receptor Monoclonal Antibody
Gene Names
CRLF2; CRL2; TSLPR; CRLF2Y
Reactivity
Human
Applications
Western Blot, Flow Cytometry, Functional Assay
Purity
Protein G Chromatography
Synonyms
TSLP Receptor, Antibody; TSLP Receptor Monoclonal Antibody; anti-CRLF2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG2a, Kappa
Clone Number
ABM28B6
Purity/Purification
Protein G Chromatography
Form/Format
25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Sequence Length
259
Applicable Applications for anti-CRLF2 antibody
WB (Western Blot), FCM/FACS (Flow Cytometry)
Immunogen
A partial lengh recombinant TSLPR protein (amino acids 97-252) was used as the immunogen for this antibody.
Preparation and Storage
Store antibody at 4 degree C, stable for 6 months. For long-term storage, store at -20 degree C. Avoid repeated freeze and thaw cycles. Expire 1 year from date of purchase.
Application Data
(Cell surface staining of THP1 cells. Green represents Isotype control. Red represents Anti-TSLP Receptor (AAA78228). 0.5 µg antibodies were used. Goat anti- mouse PE was used as secondary antibody.)
Application Data
(Cell surface staining of THP1 cells. Green represents Isotype control. Red represents Anti-TSLP Receptor (AAA78228). 0.5 µg antibodies were used. Goat anti- mouse PE was used as secondary antibody.)
WB (Western Blot)
(Western blot analysis of TSLP Receptor. Anti- TSLP Receptor antibody (Clone: ABM28B6) was tested at 2 µg/ml on (1) THP-1 and (2) human heart lysate.)
WB (Western Blot)
(Western blot analysis of TSLP Receptor. Anti- TSLP Receptor antibody (Clone: ABM28B6) was tested at 2 µg/ml on (1) THP-1 and (2) human heart lysate.)
Related Product Information for anti-CRLF2 antibody
TSLPR (thymic stromal lymphopoietin receptor) also known as CRLF2 (cytokine receptor-like factor 2) is a member of type I cytokine receptor. It binds its ligand TSLP (thymic stromal lymphopoietin) as a heterodimer with IL7R. TSLP ligand is produced by epithelial cells in order to activate dendritic cells, and is involved in inflammation, allergic responses as well as B-cell precursor proliferation and survival. The interaction between TSLP and its heterodimeric receptor activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. High expression of CRLF2 is associated with a poor prognosis in adult and high-risk pediatric cases of B-ALL (B-cell acute lymphoblastic leukemias).
Product Categories/Family for anti-CRLF2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
cytokine receptor-like factor 2 isoform 2
NCBI Official Synonym Full Names
cytokine receptor-like factor 2
NCBI Official Symbol
CRLF2
NCBI Official Synonym Symbols
CRL2; TSLPR; CRLF2Y
NCBI Protein Information
cytokine receptor-like factor 2
UniProt Protein Name
Cytokine receptor-like factor 2
UniProt Gene Name
CRLF2
UniProt Synonym Gene Names
CRL2; ILXR; TSLPR; TSLP receptor
UniProt Entry Name
CRLF2_HUMAN
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Product Notes
The CRLF2 crlf2 (Catalog #AAA78228) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TSLP Receptor Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TSLP Receptor can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the CRLF2 crlf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TSLP Receptor, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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