SDS-PAGE
(SDS PAGE for Urelumab)
anti-Human Urelumab Monoclonal Antibody | anti-TNFRSF9 antibody
Research Grade Urelumab
Gene Names
TNFRSF9; ILA; 4-1BB; CD137; CDw137
Reactivity
Human
Purity
>95%; Protein A or G purified from cell culture supernatant.
Synonyms
Urelumab, Antibody; Research Grade Urelumab; BMS-663513; Tumor necrosis factor receptor superfamily member 9; CD137; 4-1BB ligand receptor; CDw137; TNFRSF9; T-cell antigen ILA; T-cell antigen 4-1BB homolog; ILA; anti-TNFRSF9 antibody
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG4-kappa
Purity/Purification
>95%; Protein A or G purified from cell culture supernatant.
Form/Format
Liquid. PBS buffer, pH7.4
Concentration
1mg/ml (varies by lot)
Host Species
Human
CAS
934823-49-1
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at +4 degree C short term (1-2 weeks). Store at -20 degree C 12 months. Store at -80 degree C long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
SDS-PAGE
(SDS PAGE for Urelumab)
SDS-PAGE
(SDS PAGE for Urelumab)
Bioactivity
(Detects Human CD137/TNFRSF9 in direct ELISAs.)
Bioactivity
(Detects Human CD137/TNFRSF9 in direct ELISAs.)
Product Categories/Family for anti-TNFRSF9 antibody
References
Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab, PMID: 30410017
Results from an Integrated Safety Analysis of Urelumab, an Agonist Anti-CD137 Monoclonal Antibody, PMID: 27756788
Nivolumab and Urelumab Enhance Antitumor Activity of Human T Lymphocytes Engrafted in Rag2-/-IL2Rγnull Immunodeficient Mice, PMID: 26113085
Immunotherapy targeting 4-1BB: mechanistic rationale, clinical results, and future strategies, PMID: 29118009
Daratumumab in combination with urelumab to potentiate anti-myeloma activity in lymphocyte-deficient mice reconstituted with human NK cells, PMID: 31143521
Results from an Integrated Safety Analysis of Urelumab, an Agonist Anti-CD137 Monoclonal Antibody, PMID: 27756788
Nivolumab and Urelumab Enhance Antitumor Activity of Human T Lymphocytes Engrafted in Rag2-/-IL2Rγnull Immunodeficient Mice, PMID: 26113085
Immunotherapy targeting 4-1BB: mechanistic rationale, clinical results, and future strategies, PMID: 29118009
Daratumumab in combination with urelumab to potentiate anti-myeloma activity in lymphocyte-deficient mice reconstituted with human NK cells, PMID: 31143521
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27,899 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 9
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 9
NCBI Official Symbol
TNFRSF9
NCBI Official Synonym Symbols
ILA; 4-1BB; CD137; CDw137
NCBI Protein Information
tumor necrosis factor receptor superfamily member 9; CD137 antigen; T cell antigen ILA; T-cell antigen ILA; 4-1BB ligand receptor; homolog of mouse 4-1BB; receptor protein 4-1BB; T-cell antigen 4-1BB homolog; induced by lymphocyte activation (ILA); interl
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 9
UniProt Gene Name
TNFRSF9
UniProt Synonym Gene Names
CD137; ILA
UniProt Entry Name
TNR9_HUMAN
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Product Notes
The TNFRSF9 tnfrsf9 (Catalog #AAA120092) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Urelumab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Urelumab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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