Mouse anti-Human Zinc Finger Protein 846/ZNF846 Monoclonal Antibody | anti-ZNF846 antibody

Zinc Finger Protein 846/ZNF846

Cat. Num. AAA215416

• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Synonyms: Zinc Finger Protein 846/ZNF846, Antibody; Zinc Finger Protein 846/ZNF846; Zinc finger protein 846; anti-ZNF846 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2a, kappa
• Clone Number: ZNF846/2687
• Specificity: Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF846 may be involved in transcriptional regulation.
• Purity/Purification: Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Form/Format: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Sequence Length: 533

• Applicable Applications for anti-ZNF846 antibody: IHC (Immunohistochemistry)
• Immunogen: Recombinant full-length Human ZNF846 protein
• Cellular Localization: Cytoplasm
• Hu-chromosome Location: 19p13.2
• Positive Control: HeLa whole cell lysate. Prostate or breast carcinoma.
• Preparation and Storage: Antibody with azide: store at 2 to 8 degree C.; Antibody without azide: store at -20 to -80 degree C.; Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Application Data

(Analysis of Protein Array containing more than 19,000 full-length human proteins using ZNF846 Mouse Monoclonal Antibody (ZNF846/2687) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target, if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.)

SDS-PAGE

(SDS-PAGE Analysis Purified ZNF690 / ZSCAN29 Mouse Monoclonal Antibody (ZNF846/2687). Confirmation of Purity and Integrity of Antibody.)

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with ZNF690 / ZSCAN29 Mouse Monoclonal Antibody (ZNF846/2687).)

References

Bennett EJ, Rush J, Gygi SP, Harper JWBennett EJ, et al. Cell, 2010 Dec 10.

NCBI and Uniprot Product Information

• NCBI GI #: 117938301
• NCBI GeneID: 162993
• NCBI Accession #: NP_001071092.1
• NCBI GenBank Nucleotide #: NP_001071092.1
• UniProt Accession #: Q147U1
• Molecular Weight: 60.55kDa
• NCBI Official Full Name: zinc finger protein 846 isoform 1
• NCBI Official Synonym Full Names: zinc finger protein 846
• NCBI Official Symbol: ZNF846
• NCBI Protein Information: zinc finger protein 846
• UniProt Protein Name: Zinc finger protein 846
• UniProt Gene Name: ZNF846
• UniProt Entry Name: ZN846_HUMAN