Application Data
(Image: Detection of LYVE-1 in mouse spleen lysates. ECL detection overnight.)
anti-Mouse LYVE-1 Antibody | anti-LYVE-1 antibody
LYVE-1, Polyclonal Antibody, Rabbit
Gene Names
LYVE1; HAR; XLKD1; LYVE-1; CRSBP-1
Reactivity
Mouse
Applications
Western Blot, Immunohistochemistry
Synonyms
LYVE-1; N/A; LYVE-1, Polyclonal Antibody, Rabbit; anti-LYVE-1 antibody
Reactivity
Mouse
Form/Format
Affinity Purified - Liquid
Sequence Length
322
Applicable Applications for anti-LYVE-1 antibody
WB (Western Blot), IHC (Immunohistochemistry)
Type Info
Rabbit IgG
Immunogen
A synthetic peptide made to a C-terminal portion of the murine LYVE-1 protein sequence (between residues 250-318).
Application Data
(Image: Detection of LYVE-1 in mouse spleen lysates. ECL detection overnight.)
Application Data
(Image: Detection of LYVE-1 in mouse spleen lysates. ECL detection overnight.)
Application Data
(Images: LYVE-1 staining of endothelial cells of human lung blood vessels. Note presence of RBCs within vessel lumen.)
Application Data
(Images: LYVE-1 staining of endothelial cells of human lung blood vessels. Note presence of RBCs within vessel lumen.)
Related Product Information for anti-LYVE-1 antibody
The lymphatic vasculature forms a second circulatory system that drains extracellular fluid from the tissues and provides an exclusive environment in which immune cells can encounter and respond to foreign antigen. Recently a number of interesting molecules have been identified that may be exploited as markers for lymphatic endothelium, including the hyaluronan receptor LYVE1, PALE, VEGFR3, and podoplanin. LYVE1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module, the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
Product Categories/Family for anti-LYVE-1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
35,213 Da
NCBI Official Full Name
lymphatic vessel endothelial hyaluronic acid receptor 1
NCBI Official Synonym Full Names
lymphatic vessel endothelial hyaluronan receptor 1
NCBI Official Symbol
LYVE1
NCBI Official Synonym Symbols
HAR; XLKD1; LYVE-1; CRSBP-1
NCBI Protein Information
lymphatic vessel endothelial hyaluronic acid receptor 1
UniProt Protein Name
Lymphatic vessel endothelial hyaluronic acid receptor 1
UniProt Gene Name
LYVE1
UniProt Synonym Gene Names
CRSBP1; HAR; XLKD1; LYVE-1; CRSBP-1
UniProt Entry Name
LYVE1_HUMAN
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Product Notes
The LYVE-1 lyve1 (Catalog #AAA76464) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The LYVE-1, Polyclonal Antibody, Rabbit reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LYVE-1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the LYVE-1 lyve1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LYVE-1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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