Mouse Alpha-2-Antiplasmin, Serpinf2 ELISA Kit | Serpinf2 elisa kit
Mouse Alpha-2-Antiplasmin, Serpinf2 Primacu ELISA Kit
Gene Names
Serpinf2; Pli; AI747498; Serpimf2
Reactivity
Mouse
Synonyms
Alpha-2-Antiplasmin, Serpinf2; N/A; Mouse Alpha-2-Antiplasmin, Serpinf2 Primacu ELISA Kit; Alpha-2-antiplasmin; Alpha 2 Antiplasmin; Pli; Serpinf2 elisa kit
Reactivity
Mouse
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
46.88-3000pg/mL
Sensitivity
12.77pg/mL
Standard Solution
30ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C
Related Product Information for Serpinf2 elisa kit
SerpinF2, also known as alpha-2 antiplasmin (alpha-2 AP), is a member of the Serpin superfamily. SerpinF2 is the principal physiological inhibitor of serine protease plasmin, and as well as, an efficient inhibitor of trypsin and chymotrypsin. This protease is produced mainly by liver and kidney, and also expressed in muscle, intestine, central nervous system, and placenta at a moderate level. It is indicated that Serpin F2 is a key regulator of plasmin-mediated proteolysis in these tissues. Alpha-2 AP is an unusual serpin in that it contains extensive N- and C-terminal sequences flanking the serpin domain. The N-terminal sequence is crosslinked to fibrin by factor XIIIa, whereas the C-terminal region mediates the initial interaction with plasmin. SerpinF2 is one of the inhibitors of fibrinolysis, which acts as the primary inhibitor of plasmin(ogen). It is a specific plasmin inhibitor, and is important in modulating the effectiveness and persistence of fibrin with respect to its susceptibility to digestion and removal by plasmin. Alpha-2 AP plays the dominant role in inhibiting both plasma clot lysis and thrombus lysis, and accordingly, the congenital deficiency of Alpha-2 antiplasmin causes a rare bleeding disorder because of increased fibrinolysis. Thus, it may be a useful target for developing more effective treatment of thrombotic diseases.
Product Categories/Family for Serpinf2 elisa kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
160,000
NCBI Official Full Name
alpha-2-antiplasmin
NCBI Official Synonym Full Names
serine (or cysteine) peptidase inhibitor, clade F, member 2
NCBI Official Symbol
Serpinf2
NCBI Official Synonym Symbols
Pli; AI747498; Serpimf2
NCBI Protein Information
alpha-2-antiplasmin; serpin F2; alpha-2-AP; alpha-2-PI; alpha 2 antiplasmin; alpha-2-plasmin inhibitor; plasmin inhibitor alpha 2; pigment epithelium derived factor; serine (or cysteine) proteinase inhibitor, clade F, member 2
UniProt Protein Name
Alpha-2-antiplasmin
UniProt Gene Name
Serpinf2
UniProt Synonym Gene Names
Pli; Alpha-2-AP; Alpha-2-PI
UniProt Entry Name
A2AP_MOUSE
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Product Notes
The Mouse Serpinf2 serpinf2 (Catalog #AAA124219) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124219 ELISA Kit recognizes Mouse Serpinf2. It is sometimes possible for the material contained within the vial of "Alpha-2-Antiplasmin, Serpinf2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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