Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Mouse Fibroblast Growth Factor Receptor 3, Fgfr3 ELISA Kit | Fgfr3 elisa kit
Mouse Fibroblast Growth Factor Receptor 3, Fgfr3 Primacu ELISA Kit
Reactivity
Mouse
Synonyms
Fibroblast Growth Factor Receptor 3, Fgfr3; N/A; Mouse Fibroblast Growth Factor Receptor 3, Fgfr3 Primacu ELISA Kit; Fibroblast growth factor receptor 3; FGFR3; Mfr3; Sam3; Fgfr3 elisa kit
Reactivity
Mouse
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
156-10000pg/mL
Sensitivity
56.73pg/mL
Standard Solution
100ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C
Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Related Product Information for Fgfr3 elisa kit
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. FGFRs are transmembrane catalytic receptors that have intracellular tyrosine kinase activity. Mutations in FGFR genes are the cause of several human developmental disorders characterized by skeletal abnormalities such as achondroplasia, and upregulation of FGFR expression may lead to cell transformation and cancer. FGFR3, a full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of FGFR3 interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. FGFR3 binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in FGFR3 gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described. CD333 is the receptor for acidic and basic fibroblast growth factors. Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy
Product Categories/Family for Fgfr3 elisa kit
NCBI and Uniprot Product Information
UniProt Accession #
Molecular Weight
87758Da
UniProt Protein Name
Fibroblast growth factor receptor 3
UniProt Gene Name
Fgfr3
UniProt Synonym Gene Names
Mfr3; Sam3; FGFR-3
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Product Notes
The Mouse Fgfr3 fgfr3 (Catalog #AAA124111) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124111 ELISA Kit recognizes Mouse Fgfr3. It is sometimes possible for the material contained within the vial of "Fibroblast Growth Factor Receptor 3, Fgfr3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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