Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Mouse Tyrosine-Protein Kinase Receptor Ufo, Axl ELISA Kit | Axl elisa kit
Mouse Tyrosine-Protein Kinase Receptor Ufo, Axl Primacu ELISA Kit
Gene Names
Axl; Ark; Ufo; Tyro7; AI323647
Reactivity
Mouse
Synonyms
Tyrosine-Protein Kinase Receptor Ufo, Axl; N/A; Mouse Tyrosine-Protein Kinase Receptor Ufo, Axl Primacu ELISA Kit; Tyrosine-protein kinase receptor UFO; AXL; Ark; Ufo; Axl elisa kit
Reactivity
Mouse
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
12.5-800pg/mL
Sensitivity
2.52pg/mL
Standard Solution
8ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C
Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Related Product Information for Axl elisa kit
Axl receptor tyrosine kinase, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific protein 6 (Gas6) are expressed on multiple cell types. Axl functions in dampening the immune response, regulating cytokine secretion, clearing apoptotic cells and debris, and maintaining cell survival. Axl is upregulated in various disease states, such as in the cuprizone toxicity-induced model of demyelination and in multiple sclerosis (MS) lesions, suggesting that it plays a role in disease pathogenesis. Axl expression correlates with poor prognosis in several cancers. Axl mediates multiple oncogenic phenotypes and activation of these RTKs constitutes a mechanism of chemoresistance in a variety of solid tumors. Axl contributes to cell survival, migration, invasion, metastasis and chemosensitivity justify further investigation of Axl as novel therapeutic targets in cancer. The receptor tyrosine kinase AXL is thought to play a role in metastasis. The soluble AXL receptor as a therapeutic candidate agent for treatment of metastatic ovarian cancer. GAS6/AXL targeting as an effective strategy for inhibition of metastatic tumor progression in vivo.
Product Categories/Family for Axl elisa kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
98,191 Da
NCBI Official Full Name
Tyrosine-protein kinase receptor UFO
NCBI Official Synonym Full Names
AXL receptor tyrosine kinase
NCBI Official Symbol
Axl
NCBI Official Synonym Symbols
Ark; Ufo; Tyro7; AI323647
NCBI Protein Information
tyrosine-protein kinase receptor UFO; ufo oncogene homolog; adhesion-related kinase
UniProt Protein Name
Tyrosine-protein kinase receptor UFO
UniProt Gene Name
Axl
UniProt Synonym Gene Names
Ark; Ufo
UniProt Entry Name
UFO_MOUSE
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Product Notes
The Mouse Axl axl (Catalog #AAA124357) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124357 ELISA Kit recognizes Mouse Axl. It is sometimes possible for the material contained within the vial of "Tyrosine-Protein Kinase Receptor Ufo, Axl, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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