Application Data
Mouse anti-Human BPTF Antibody | anti-BPTF antibody
BPTF Antibody
Gene Names
BPTF; FAC1; FALZ; NEDDFL; NURF301
Reactivity
Human
Applications
ELISA, Western Blot
Synonyms
BPTF; N/A; BPTF Antibody; FAC1; FALZ; NURF301; anti-BPTF antibody
Host
Mouse
Reactivity
Human
Isotype
IgG1
Clone Number
2F10
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
2903
Applicable Applications for anti-BPTF antibody
ELISA, WB (Western Blot)
Immunogen
Purified recombinant fragment (503-670aa) of human BPTF expressed in E. Coli.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C.
Application Data
Application Data
WB (Western Blot)
(Figure 1: Western blot analysis using BPTF mAb against HEK293 (1) and BPTF-hIgGFc transfected HEK293 (2) cell lysate.)
WB (Western Blot)
(Figure 1: Western blot analysis using BPTF mAb against HEK293 (1) and BPTF-hIgGFc transfected HEK293 (2) cell lysate.)
Related Product Information for anti-BPTF antibody
BPTF (bromodomain and PHD domain transcription factor) is the largest subunit of the ATP-dependent chromatin-remodelling complex, NURF (nucleosome remodelling factor). NURF catalyses ATP-dependent nucleosome sliding and facilitates transcription. BPTF recognises histone H3 tails that are tri-methylated at K4, which marks the transcriptional start site of the vast majority of transcriptionally active genes. BPTF also exhibits some binding to H3 di-methylated at K4. BPTF plays a key role in the development of early mouse embryos, possibly through regulation of the Smad pathway of transcription factors. While BPTF is expressed in low levels in the adult brain and spinal cord, it is expressed in higher levels in the brain in neurodegenerative diseases. It is present in a subset of amyloid-containing plaques in the brains of patients suffering from Alzheimer's disease. Abundantly expressed in the fetal brain. Present throughout the gray and white matter of the developing spinal cord at 18-22 gestational weeks. Expressed at low levels in adult brain and spinal cord and reexpressed in neurodegenerative diseases (at protein level).Tissue specificity: Ubiquitously expressed, with highest levels in testis. Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex (at protein level).
Product Categories/Family for anti-BPTF antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
338kDa
NCBI Official Full Name
nucleosome-remodeling factor subunit BPTF isoform 2
NCBI Official Synonym Full Names
bromodomain PHD finger transcription factor
NCBI Official Symbol
BPTF
NCBI Official Synonym Symbols
FAC1; FALZ; NEDDFL; NURF301
NCBI Protein Information
nucleosome-remodeling factor subunit BPTF
UniProt Protein Name
Nucleosome-remodeling factor subunit BPTF
UniProt Gene Name
BPTF
UniProt Synonym Gene Names
FAC1; FALZ
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Product Notes
The BPTF bptf (Catalog #AAA108519) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The BPTF Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BPTF can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the BPTF bptf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BPTF, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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