Application Data
(Figure 2. Immunohistochemical analysis of paraffin-embedded human gastric adenocarcinoma(A), colon adenocarcinoma(B), endometrial carcinoma(uterus)(C), ovary adenocarcinoma(D), lung squamous cell carcinoma(E), stomach epithelium mucosae(F), showing membrane localization using IGF1R mouse mAb with DAB staining.)
Mouse anti-Human IGF1R Antibody | anti-IGF1R antibody
IGF1R Antibody
Gene Names
IGF1R; IGFR; CD221; IGFIR; JTK13
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Synonyms
IGF1R; N/A; IGF1R Antibody; anti-IGF1R antibody
Host
Mouse
Reactivity
Human
Isotype
IgG2b
Clone Number
3C8B1
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
1367
Applicable Applications for anti-IGF1R antibody
ELISA, IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Purified recombinant fragment of IGF1R expressed in E. Coli.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C
Application Data
(Figure 2. Immunohistochemical analysis of paraffin-embedded human gastric adenocarcinoma(A), colon adenocarcinoma(B), endometrial carcinoma(uterus)(C), ovary adenocarcinoma(D), lung squamous cell carcinoma(E), stomach epithelium mucosae(F), showing membrane localization using IGF1R mouse mAb with DAB staining.)
Application Data
(Figure 2. Immunohistochemical analysis of paraffin-embedded human gastric adenocarcinoma(A), colon adenocarcinoma(B), endometrial carcinoma(uterus)(C), ovary adenocarcinoma(D), lung squamous cell carcinoma(E), stomach epithelium mucosae(F), showing membrane localization using IGF1R mouse mAb with DAB staining.)
Application Data
(Figure 1. Western blot analysis using IGF1R mouse mAb against truncated IGF1R recombinant protein.)
Application Data
(Figure 1. Western blot analysis using IGF1R mouse mAb against truncated IGF1R recombinant protein.)
Related Product Information for anti-IGF1R antibody
IGF1R (insulin-like growth factor 1 receptor), a transmembrane receptor tyrosine kinase, is widely expressed in many cell types within fetal and postnatal tissues, and in many cell lines. Upon binding to its ligands, IGF-I and IGF-II, receptor autophosphorylation occurs. The triple tyrosine cluster within the kinase domain (Tyr1131, Tyr1135 and Tyr1136) is the earliest major site of autophosphorylation. Phosphorylation of these three tyrosine residues is necessary for kinase activation.Insulin receptors (IRs) share significant similarity with IGF1 receptors in both structure and function, including an equivalent triple tyrosine cluster within the activation loop of the kinase domain (Tyr1146, Tyr1150 and Tyr1151).Tyrosine autophosphorylation of insulin receptor is one of the earliest cellular responses to insulin stimulation. Autophosphorylation begins with phosphorylation of Tyr1146 and either Tyr1150 or Tyr1151. Full kinase activation requires the triple tyrosine phosphorylation.
Product Categories/Family for anti-IGF1R antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
154,793 Da
NCBI Official Full Name
insulin-like growth factor 1 receptor isoform 1
NCBI Official Synonym Full Names
insulin like growth factor 1 receptor
NCBI Official Symbol
IGF1R
NCBI Official Synonym Symbols
IGFR; CD221; IGFIR; JTK13
NCBI Protein Information
insulin-like growth factor 1 receptor
UniProt Protein Name
Insulin-like growth factor 1 receptor
UniProt Gene Name
IGF1R
UniProt Synonym Gene Names
IGF-I receptor
Similar Products
Product Notes
The IGF1R igf1r (Catalog #AAA108696) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The IGF1R Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IGF1R can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the IGF1R igf1r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IGF1R, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.