IF (Immunofluorescence)
(Figure 2. Confocal immunofluorescence analysis of HEK293 cells trasfected with extracellular MUSK (aa24-209)-hIgGFc using MUSK mouse mAb (green). Blue. DRAQ5 fluorescent DNA dye.)
Mouse anti-Human MUSK Antibody | anti-MUSK antibody
MUSK Antibody
Gene Names
MUSK; CMS9; FADS
Reactivity
Human
Applications
ELISA, Immunofluorescence, Immunohistochemistry
Synonyms
MUSK; N/A; MUSK Antibody; muscle; skeletal; receptor tyrosine kinase; anti-MUSK antibody
Host
Mouse
Reactivity
Human
Isotype
IgG1
Clone Number
10A4
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
783
Applicable Applications for anti-MUSK antibody
ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry)
Immunogen
Purified recombinant extracellular fragment of human MUSK (aa24-209) fused with hIgGFc tag expressed in HEK293 cell line.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C
IF (Immunofluorescence)
(Figure 2. Confocal immunofluorescence analysis of HEK293 cells trasfected with extracellular MUSK (aa24-209)-hIgGFc using MUSK mouse mAb (green). Blue. DRAQ5 fluorescent DNA dye.)
IF (Immunofluorescence)
(Figure 2. Confocal immunofluorescence analysis of HEK293 cells trasfected with extracellular MUSK (aa24-209)-hIgGFc using MUSK mouse mAb (green). Blue. DRAQ5 fluorescent DNA dye.)
IHC (Immunohistochemistry)
(Figure 1. Immunohistochemical analysis of paraffin-embedded human lung cancer (A), muscles (B) and breast cancer (C) using MUSK mouse mAb with DAB staining.)
IHC (Immunohistochemistry)
(Figure 1. Immunohistochemical analysis of paraffin-embedded human lung cancer (A), muscles (B) and breast cancer (C) using MUSK mouse mAb with DAB staining.)
Related Product Information for anti-MUSK antibody
MuSK (for Muscle Specific Kinase) is a receptor tyrosine kinase required for the formation of the neuromuscular junction (NMJ). It induces cellular signaling by causing the addition of phosphate molecules to particular tyrosines on itself, and on proteins which bind the cytoplasmic domain of the receptor. It is activated by a nerve-derived proteoglycan called agrin. During development, the growing end of motor neuron axons secrete a protein called agrin. This protein binds to several receptors on the surface of skeletal muscle. The receptor which seems to be required for formation of the neuromuscular junction (NMJ), which comprises the nerve-muscle synapse is called MuSK. MUSK mutations lead to decreased agrin-dependent AchR aggregation, a critical step in the formation of the neuromuscular junction.
Product Categories/Family for anti-MUSK antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
97kDa
NCBI Official Full Name
muscle, skeletal receptor tyrosine-protein kinase isoform 2
NCBI Official Synonym Full Names
muscle associated receptor tyrosine kinase
NCBI Official Symbol
MUSK
NCBI Official Synonym Symbols
CMS9; FADS
NCBI Protein Information
muscle, skeletal receptor tyrosine-protein kinase
UniProt Protein Name
Muscle, skeletal receptor tyrosine-protein kinase
UniProt Gene Name
MUSK
UniProt Synonym Gene Names
MuSK; Muscle-specific kinase receptor
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Product Notes
The MUSK musk (Catalog #AAA108541) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MUSK Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MUSK can be used in a range of immunoassay formats including, but not limited to, ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the MUSK musk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MUSK, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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