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product-image-AAA108414_AD11.jpg Application Data

Mouse CRTC3 Antibody | anti-CRTC3 antibody

CRTC3 Antibody

Gene Names
CRTC3; TORC3; TORC-3
Reactivity
Human, Monkey
Applications
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Synonyms
CRTC3; N/A; CRTC3 Antibody; TORC3; FLJ21868; anti-CRTC3 antibody
Ordering
Host
Mouse
Reactivity
Human, Monkey
Isotype
IgG1
Clone Number
5G9
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
618
Applicable Applications for anti-CRTC3 antibody
ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Purified recombinant fragment of human CRTC3 expressed in E. Coli.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C.

Application Data

product-image-AAA108414_AD11.jpg Application Data

IHC (Immunohiostchemistry)

(Figure 2: Immunohistochemical analysis of paraffin-embedded breast cancer (left) and ovarian cancer (right) using CRTC3 mouse mAb with DAB staining.)

product-image-AAA108414_IHC13.jpg IHC (Immunohiostchemistry) (Figure 2: Immunohistochemical analysis of paraffin-embedded breast cancer (left) and ovarian cancer (right) using CRTC3 mouse mAb with DAB staining.)

WB (Western Blot)

(Figure 1: Western blot analysis using CRTC3 mouse mAb against Hela (1), Jurkat (2), Cos7 (3) and MCF-7 (4) cell lysate.)

product-image-AAA108414_WB15.jpg WB (Western Blot) (Figure 1: Western blot analysis using CRTC3 mouse mAb against Hela (1), Jurkat (2), Cos7 (3) and MCF-7 (4) cell lysate.)
Related Product Information for anti-CRTC3 antibody
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
68kDa
NCBI Official Full Name
CREB-regulated transcription coactivator 3 isoform b
NCBI Official Synonym Full Names
CREB regulated transcription coactivator 3
NCBI Official Symbol
CRTC3
NCBI Official Synonym Symbols
TORC3; TORC-3
NCBI Protein Information
CREB-regulated transcription coactivator 3
UniProt Protein Name
CREB-regulated transcription coactivator 3
UniProt Gene Name
CRTC3
UniProt Synonym Gene Names
TORC3; TORC-3; Transducer of CREB protein 3

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Product Notes

The CRTC3 crtc3 (Catalog #AAA108414) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CRTC3 Antibody reacts with Human, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's CRTC3 can be used in a range of immunoassay formats including, but not limited to, ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CRTC3 crtc3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CRTC3, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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