FCM/FACS (Flow Cytometry)
(Figure 3. Flow cytometric analysis of Hela cells using Metadherin mouse mAb (green) and negative control (purple).)
Mouse anti-Human Metadherin Antibody | anti-MTDH antibody
Metadherin Antibody
Gene Names
MTDH; 3D3; AEG1; AEG-1; LYRIC; LYRIC/3D3
Reactivity
Human
Applications
ELISA, Flow Cytometry, Functional Assay, Immunohistochemistry, Western Blot
Synonyms
Metadherin; N/A; Metadherin Antibody; 3D3; AEG1; LYRIC; anti-MTDH antibody
Host
Mouse
Reactivity
Human
Isotype
IgG1
Clone Number
2F11C3
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
582
Applicable Applications for anti-MTDH antibody
ELISA, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Purified recombinant fragment of human Metadherin expressed in E. Coli.
Preparation and Storage
Store at 4°C, for long term storage, store at -20°C
FCM/FACS (Flow Cytometry)
(Figure 3. Flow cytometric analysis of Hela cells using Metadherin mouse mAb (green) and negative control (purple).)
FCM/FACS (Flow Cytometry)
(Figure 3. Flow cytometric analysis of Hela cells using Metadherin mouse mAb (green) and negative control (purple).)
IHC (Immunohiostchemistry)
(Figure 2. Immunohistochemical analysis of paraffin-embedded human Liver tissues using Metadherin mouse mAb)
IHC (Immunohiostchemistry)
(Figure 2. Immunohistochemical analysis of paraffin-embedded human Liver tissues using Metadherin mouse mAb)
WB (Western Blot)
(Figure 1. Western blot analysis using Metadherin mouse mAb against K562 (1), SKBR-3 (2), T47D (3), Hela (4) and MCF-7 (5) cell lysate.)
WB (Western Blot)
(Figure 1. Western blot analysis using Metadherin mouse mAb against K562 (1), SKBR-3 (2), T47D (3), Hela (4) and MCF-7 (5) cell lysate.)
Related Product Information for anti-MTDH antibody
Metadherin (Metastasis adhesion protein), also known as MTDH, LYsine-RIch CEACAM1 co-isolated (LYRIC), is a novel protein that localizes with the tight junction proteins ZO-1 and occludin in polarized epithelial cells. At the tight junction, it acts not as a structural component, but is rather recruited during the maturation of the tight junction complex. Metadherin is overexpressed in breast cancer tissue and breast tumor xenografts, while much lower levels are expressed in normal breast tissue. Metadherin binds to lung vasculature, one of the four common sites of breast cancer metastasis, through a C-terminal segment in the extracellular domain; blocking this lung-homing domain with antibodies or inhibiting metadherin with siRNA has been reported to inhibit breast cancer metastasis.
Product Categories/Family for anti-MTDH antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
64kDa
NCBI Official Full Name
protein LYRIC isoform 1
NCBI Official Synonym Full Names
metadherin
NCBI Official Symbol
MTDH
NCBI Official Synonym Symbols
3D3; AEG1; AEG-1; LYRIC; LYRIC/3D3
NCBI Protein Information
protein LYRIC
UniProt Protein Name
Protein LYRIC
UniProt Gene Name
MTDH
UniProt Synonym Gene Names
AEG1; LYRIC; AEG-1
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Product Notes
The MTDH mtdh (Catalog #AAA108642) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Metadherin Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Metadherin can be used in a range of immunoassay formats including, but not limited to, ELISA, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the MTDH mtdh for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Metadherin, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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