Murine sRANK Ligand ELISA Kit | sRANK elisa kit

Murine sRANK Ligand Pre-Coated ELISA Kit

Cat. Num. AAA79410

• Gene Names: Tnfsf11; ODF; OPG; OPGL; RANKL; Ly109l; Trance
• Reactivity: Murine
• Synonyms: sRANK Ligand; N/A; Murine sRANK Ligand Pre-Coated ELISA Kit; sRANK elisa kit

• Reactivity: Murine
• Specificity: Natural and recombinant Murine sRANK Ligand
• Assay Type: Solid Phase Sandwich ELISA: 96-Well Strip Plate
• Detection Range: 15.6pg/ml-1000pg/ml
• Sensitivity: <10pg/ml
• Components: Anti-Murine sRANK Ligand Pre-coated 96-well strip microplate; Murine sRANK Ligand Standard; Murine sRANK Ligand Biotinylated antibody (100x); Avidin-Biotin-Peroxidase Complex (100x); Sample Diluent; Antibody Diluent; Avidin-Biotin-Peroxidase Diluent; Wash Buffer Concentrate (Powder for 1000mL); Color Developing Reagent; Stop Solution; Plate Sealers
• Interference: No detectable cross-reactivity with other relevant proteins

• Preparation and Storage: Store the unopened product at 2-8 degree C.

Standard Curve (Sample)

Related Product Information for sRANK elisa kit

RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic cell-membrane protein, which, by interacting with RANKL, augments the ability of dendritic cells. These dendritic cells then stimulate naïve T-cell proliferation in a mixed lymphocyte reaction, promote the survival of RANK + T-cells, and regulate T-cell-dependent immune response. RANKL, which is expressed in a variety of cells, including osteoblasts, fibroblasts, activated T-cells and bone marrow stromal cells, is also capable of interacting with a decoy receptor called OPG. Binding of soluble OPG to sRANKL inhibits osteoclastogenesis by interrupting the signaling between stromal cells and osteoclastic progenitor cells, thereby leading to excess accumulation of bone and cartilage.
Murine sRANK Ligand Pre-Coated ELISA (Enzyme-Linked Immunosorbent Assay) kit is a solid phase immunoassay specially designed to measure sRANK Ligand with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for sRANK Ligand. It contains NS0-expressed recombinant sRANK Ligand. The detection antibody is a biotinylated goat polyclonal antibody specific for sRANK Ligand. The kit is analytically validated with ready to use reagents.

NCBI and Uniprot Product Information

• NCBI GI #: 114842415
• NCBI GeneID: 21943
• NCBI Accession #: NP_035743.2
• NCBI GenBank Nucleotide #: NM_011613.3
• UniProt Accession #: O35235; O35306; Q3TWY5; Q9JJK8; Q9JJK9; Q9R1Y0
• Molecular Weight: 35,003 Da
• NCBI Official Full Name: tumor necrosis factor ligand superfamily member 11
• NCBI Official Synonym Full Names: tumor necrosis factor (ligand) superfamily, member 11
• NCBI Official Symbol: Tnfsf11
• NCBI Official Synonym Symbols: ODF; OPG; OPGL; RANKL; Ly109l; Trance
• NCBI Protein Information: tumor necrosis factor ligand superfamily member 11; OPG ligand; osteoprotegerin ligand; osteoclast differentiation factor; receptor activator of NF-kappaB ligand; TNF-related activation-induced cytokine; receptor activator of nuclear factor kappa B ligand
• UniProt Protein Name: Tumor necrosis factor ligand superfamily member 11
• UniProt Gene Name: Tnfsf11
• UniProt Synonym Gene Names: Opgl; Rankl; Trance; ODF; OPGL; RANKL; TRANCE
• UniProt Entry Name: TNF11_MOUSE