Pro-neuregulin-1, membrane-bound isoform ELISA Kit | NRG1 elisa kit
Human Neuregulin-1/NRG1-beta1 PicoKine ELISA Kit
Gene Names
NRG1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2
Reactivity
Human. There is no detectable cross-reactivity with other relevant proteins.
Synonyms
Pro-neuregulin-1, membrane-bound isoform; N/A; Human Neuregulin-1/NRG1-beta1 PicoKine ELISA Kit; Acetylcholine receptor inducing activity; Acetylcholine receptor-inducing activity; ARIA; Breast cancer cell differentiation factor p45; GGF; GGF2; Glial growth factor; Heregulin; HGL; HRG; HRG1; HRGA; MST131; NDF; Neu differentiation factor; Neuregulin 1; Neuregulin-1; Neuregulin1; nrg1; NRG1 beta 1; NRG1_HUMAN; Pro neuregulin 1; Pro NRG1; Pro-NRG1; Sensory and motor neuron derived factor; Sensory and motor neuron-derived factor; SMDF; neuregulin 1; NRG1 elisa kit
Reactivity
Human. There is no detectable cross-reactivity with other relevant proteins.
Sequence Length
607
Samples
Cell culture supernates, serum and plasma (heparin, EDTA)
Assay Type
Sandwich
Sensitivity
<10pg/ml
Immunogen
E.coli, S2-K246
Intra-Assay Precision
Sample 1: n=16; Mean(pg/ml): 675; Standard deviation: 28.35; CV(%): 4.2 Sample 2: n=16; Mean(pg/ml): 1308; Standard deviation: 61.48; CV(%): 4.7 Sample 3: n=16; Mean(pg/ml): 2147; Standard deviation: 113.8; CV(%): 5.3
Inter-Assay Precision
Sample 1: n=24; Mean(pg/ml): 694; Standard deviation: 40.25; CV(%): 5.8 Sample 2: n=24; Mean(pg/ml): 1382; Standard deviation: 84.3; CV(%): 6.1 Sample 3: n=24; Mean(pg/ml): 2503; Standard deviation: 172.7; CV(%): 6.9
Assay Range
62.5pg/ml-4000pg/ml
Preparation and Storage
Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Related Product Information for NRG1 elisa kit
Description: Sandwich ELISA kit of Quantitative Detection for Human Neuregulin-1/NRG1-beta1
Background: Neuregulin 1 or NRG1 is a protein that in humans is encoded by the NRG1 gene. It is mapped to 8p12. NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). It is also essential for the normal development of the nervous system and the heart. Furthermore, it was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues.
Background: Neuregulin 1 or NRG1 is a protein that in humans is encoded by the NRG1 gene. It is mapped to 8p12. NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). It is also essential for the normal development of the nervous system and the heart. Furthermore, it was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,226 Da
NCBI Official Full Name
pro-neuregulin-1, membrane-bound isoform isoform HRG-beta1c
NCBI Official Synonym Full Names
neuregulin 1
NCBI Official Symbol
NRG1
NCBI Official Synonym Symbols
GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2
NCBI Protein Information
pro-neuregulin-1, membrane-bound isoform; pro-NRG1; glial growth factor; neu differentiation factor; sensory and motor neuron derived factor; heregulin, alpha (45kD, ERBB2 p185-activator)
UniProt Protein Name
Pro-neuregulin-1, membrane-bound isoform
UniProt Gene Name
NRG1
UniProt Synonym Gene Names
GGF; HGL; HRGA; NDF; SMDF; Pro-NRG1; ARIA; HRG
UniProt Entry Name
NRG1_HUMAN
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Product Notes
The Human. There is no detectable cross-reactivity with other relevant proteins. NRG1 nrg1 (Catalog #AAA46109) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA46109 ELISA Kit recognizes Human. There is no detectable cross-reactivity with other relevant proteins. NRG1. It is sometimes possible for the material contained within the vial of "Pro-neuregulin-1, membrane-bound isoform, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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