Standard Curve (Sample)
Mouse paired box 6 ELISA Kit | PAX6 elisa kit
Mouse paired box 6, PAX6 ELISA Kit
Standard Curve (Sample)
Standard Curve (Sample)
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Product Notes
The Mouse PAX6 pax6 (Catalog #AAA18043) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA18043 ELISA Kit recognizes Mouse PAX6. It is sometimes possible for the material contained within the vial of "paired box 6, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Frequently Asked Questions
What does a PAX6 ELISA kit measure in biological samples?
This kit measures endogenous human PAX6 (Paired Box Gene 6) protein concentration - a transcription factor critical for ocular and neural development. The assay specifically detects native PAX6 protein, enabling researchers to quantify PAX6 expression levels in tissue and cell-derived samples for developmental and disease studies.
Is PAX6 a marker for stem cell or neural development studies?
Yes, PAX6 is a master regulator of neural and ocular development. Elevated PAX6 expression correlates with neural progenitor cell maintenance and differentiation, making it an essential marker for studying stem cell differentiation, neural development, and retinal development in research models.
Which sample types are compatible with a PAX6 ELISA assay?
Compatible samples include tissue homogenates from neural or ocular tissues, cell lysates from cultured neural/retinal cells, cell culture supernatants, plasma, and serum. Samples should be prepared according to protocol to preserve PAX6 protein integrity and immunoreactivity.
Can a PAX6 ELISA kit be used to monitor eye or brain development research?
Yes, PAX6 ELISA is directly applicable to eye and brain development research. PAX6 expression levels serve as quantitative readouts for retinal differentiation, optic nerve development, and cortical neurogenesis and can track developmental progression or abnormalities in differentiation protocols.
How is PAX6 expression linked to diseases like aniridia or neurodevelopmental disorders?
PAX6 mutations or reduced expression cause aniridia (congenital eye absence) and various neurodevelopmental disorders, including cognitive impairment and seizure susceptibility. Measuring PAX6 levels helps identify developmental defects and can serve as a biomarker for assessing disease severity or therapeutic intervention efficacy.
What controls or standards are needed for accurate PAX6 ELISA quantification?
Standard PAX6 recombinant protein standards and appropriate positive/negative tissue controls (e.g., PAX6-expressing neural tissue vs. non-neural tissue controls) are essential. Blank wells and reference samples ensure accurate standard curve generation and reliable quantification.
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