Structure
(NCT-504, CAS 1222765-97-0)
PKA Inhibitor (5-24)(trifluoroacetate salt) Biochemical | PKA-IN-1 biochemical
PKA Inhibitor (5-24)(trifluoroacetate salt)
Purity
98%
Synonyms
PKA Inhibitor (5-24)(trifluoroacetate salt); N/A; PKA-IN-1 biochemical
Purity/Purification
98%
Solubility
PBS (pH 7.2): 2 mg/mL
DMSO: 1 mg/mL
<1mg/ml refers to the product slightly soluble or insoluble
DMSO: 1 mg/mL
<1mg/ml refers to the product slightly soluble or insoluble
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(NCT-504, CAS 1222765-97-0)
Structure
(NCT-504, CAS 1222765-97-0)
Structure
(NCT-504, CAS 1222765-97-0)
Structure
(NCT-504, CAS 1222765-97-0)
Related Product Information for PKA-IN-1 biochemical
PKI PKA Inhibitor (5-24) is a synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase)(Ki= 2.3 nM) derived from the active site of the skeletal muscle inhibitor protein.1It mimics the protein substrate by binding to the catalytic site through the arginine-cluster basic subsite.1The prominent enzyme-substrate interaction site occurs where PKA catalytic subunit residues Tyr235and Phe239form a sandwich-like structure with residue Phe10of PKI (5-24).2
References
1. Ismael Al-Ramahi, et al. Inhibition of PIP4Kgamma Ameliorates the Pathological Effects of Mutant Huntingtin Protein. Elife. 2017 Dec 26;6:e29123.
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Product Notes
The PKA-IN-1 (Catalog #AAA227101) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PKA Inhibitor (5-24)(trifluoroacetate salt), Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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