ICC (Immunocytochemistry)
(Immunocytochemistry of Acinus in K562 cells with Acinus antibody at 0.5 ug/mL.)
Rabbit anti-Human Acinus Polyclonal Antibody | anti-ACIN1 antibody
Acinus Antibody
Gene Names
ACIN1; ACN; ACINUS; fSAP152
Reactivity
Human
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
Acinus, Antibody; Acinus Antibody; anti-ACIN1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
1341
Applicable Applications for anti-ACIN1 antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a peptide corresponding to amino acids near the carbosy terminus of human AcinusL, which are identical to those of mouse Acinus.
Target Name
Acinus
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of Acinus in K562 cells with Acinus antibody at 0.5 ug/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of Acinus in K562 cells with Acinus antibody at 0.5 ug/mL.)
WB (Western Blot)
(Western blot analysis of Acinus in K562 whole cell lysate with Acinus antibody at 0.5 ug/mL.)
WB (Western Blot)
(Western blot analysis of Acinus in K562 whole cell lysate with Acinus antibody at 0.5 ug/mL.)
Related Product Information for anti-ACIN1 antibody
Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS'.
Product Categories/Family for anti-ACIN1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
150,557 Da
NCBI Official Full Name
acinusL
NCBI Official Synonym Full Names
apoptotic chromatin condensation inducer 1
NCBI Official Symbol
ACIN1
NCBI Official Synonym Symbols
ACN; ACINUS; fSAP152
NCBI Protein Information
apoptotic chromatin condensation inducer in the nucleus
UniProt Protein Name
Apoptotic chromatin condensation inducer in the nucleus
UniProt Gene Name
ACIN1
UniProt Synonym Gene Names
ACINUS; KIAA0670; Acinus
UniProt Entry Name
ACINU_HUMAN
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Product Notes
The ACIN1 acin1 (Catalog #AAA306612) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Acinus Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Acinus can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the ACIN1 acin1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Acinus, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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