Rabbit anti-Human Acinus Polyclonal Antibody | anti-ACIN1 antibody

Acinus Antibody

Cat. Num. AAA39473

• Gene Names: ACIN1; ACN; ACINUS; fSAP152
• Reactivity: Human
• Applications: Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
• Purity: Acinus Antibody is affinity chromatography purified via peptide column.
• Synonyms: Acinus, Antibody; Acinus Antibody; ACN; ACINUS; fSAP152; KIAA0670; Apoptotic chromatin condensation inducer in the nucleus; Acinus; apoptotic chromatin condensation inducer 1; anti-ACIN1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Acinus Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Sequence Length: 1341

• Applicable Applications for anti-ACIN1 antibody: IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: Acinus antibody was raised against a peptide corresponding to amino acids near the C-terminus of the cleaved active peptide p17, which are identical to those of mouse Acinus.
• Buffer: Acinus Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: Acinus antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of Acinus in K562 cells with Acinus antibody at 20 μg/ml.Green: Acinus Antibody (2215)Blue: DAPI staining)

IF (Immunofluorescence)

(Immunofluorescence of Acinus in Hela cells with Acinus antibody at 10 μg/mL.)

ICC (Immunocytochemistry)

(Immunocytochemistry staining of K562 cells using Acinus antibody at 10 μg/mL.)

WB (Western Blot)

(Western blot analysis of Acinus in K562 whole cell lysate with Acinus antibody (CP) at 1 μg/mL.)

Related Product Information for anti-ACIN1 antibody

Acinus Antibody: Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS'.

NCBI and Uniprot Product Information

• NCBI GI #: 5931959
• NCBI GeneID: 22985
• UniProt Accession #: Q9UKV3; O75158; Q9UG91; Q9UKV1; Q9UKV2; B2RTT4; D3DS45
• Molecular Weight: 220 kDa
• NCBI Official Full Name: acinusL
• NCBI Official Synonym Full Names: apoptotic chromatin condensation inducer 1
• NCBI Official Symbol: ACIN1
• NCBI Official Synonym Symbols: ACN; ACINUS; fSAP152
• NCBI Protein Information: apoptotic chromatin condensation inducer in the nucleus; functional spliceosome-associated protein 152
• UniProt Protein Name: Apoptotic chromatin condensation inducer in the nucleus
• UniProt Gene Name: ACIN1
• UniProt Synonym Gene Names: ACINUS; KIAA0670; Acinus
• UniProt Entry Name: ACINU_HUMAN