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product-image-AAA233916_IF10.jpg IF (Immunofluorescence) (Immunofluorescent analysis of Hela cells using AAA233916 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Rabbit anti-Human ACO1 Polyclonal Antibody | anti-ACO1 antibody

ACO1 Antibody

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Gene Names
ACO1; IRP1; ACONS; HEL60; IREB1; IREBP; IREBP1
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
>95%, Protein G purified
Synonyms
ACO1, Antibody; ACO1 Antibody; Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1; ACO1; IREB1; anti-ACO1 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
889
Applicable Applications for anti-ACO1 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen
Recombinant Human Cytoplasmic aconitate hydratase protein (508-745AA)
Conjugation
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

IF (Immunofluorescence)

(Immunofluorescent analysis of Hela cells using AAA233916 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

product-image-AAA233916_IF10.jpg IF (Immunofluorescence) (Immunofluorescent analysis of Hela cells using AAA233916 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

IHC (Immunohistochemisry)

(Immunohistochemistry of paraffin-embedded human small intestine tissue using AAA233916 at dilution of 1:100)

product-image-AAA233916_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemistry of paraffin-embedded human small intestine tissue using AAA233916 at dilution of 1:100)

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded human kidney tissue using AAA233916 at dilution of 1:100)

product-image-AAA233916_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of paraffin-embedded human kidney tissue using AAA233916 at dilution of 1:100)

WB (Western Blot)

(Western BlotPositive WB detected in: HepG2 whole cell lysate, Hela whole cell lysateAll lanes: ACO1 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 99 KDaObserved band size: 99 KDa)

product-image-AAA233916_WB15.jpg WB (Western Blot) (Western BlotPositive WB detected in: HepG2 whole cell lysate, Hela whole cell lysateAll lanes: ACO1 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 99 KDaObserved band size: 99 KDa)
Related Product Information for anti-ACO1 antibody
Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
48
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
98,399 Da
NCBI Official Full Name
cytoplasmic aconitate hydratase
NCBI Official Synonym Full Names
aconitase 1
NCBI Official Symbol
ACO1
NCBI Official Synonym Symbols
IRP1; ACONS; HEL60; IREB1; IREBP; IREBP1
NCBI Protein Information
cytoplasmic aconitate hydratase
UniProt Protein Name
Cytoplasmic aconitate hydratase
UniProt Gene Name
ACO1
UniProt Synonym Gene Names
IREB1; Aconitase; IRP1; IRE-BP 1

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Product Notes

The ACO1 aco1 (Catalog #AAA233916) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ACO1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ACO1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the ACO1 aco1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ACO1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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