IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin-embedded human stomach cancer using AFP antibody at dilution of 1:200 (200x lens).)
Rabbit AFP Polyclonal Antibody | anti-AFP antibody
AFP Antibody
Gene Names
AFP; AFPD; FETA; HPAFP
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Antibodies were purified by affinity purification using immunogen.
Synonyms
AFP, Antibody; AFP Antibody; AFP; FETA; Alphafetoglobulin; alphafetoprotein; Alpha1fetoprotein; anti-AFP antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total AFP protein.
Purity/Purification
Antibodies were purified by affinity purification using immunogen.
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
609
Applicable Applications for anti-AFP antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
A synthetic peptide of human AFP.
Target Name
AFP
Preparation and Storage
Store at -20 degree C
IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin-embedded human stomach cancer using AFP antibody at dilution of 1:200 (200x lens).)
IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin-embedded human stomach cancer using AFP antibody at dilution of 1:200 (200x lens).)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human bladder cancer using AFP antibody at dilution of 1:200 (200x lens).)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human bladder cancer using AFP antibody at dilution of 1:200 (200x lens).)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using AFP antibody.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using AFP antibody.)
Related Product Information for anti-AFP antibody
Alpha-fetoprotein (AFP) is a 65 kDa glycoprotein found in the serum of the mammalian fetal liver, yolk sac, and GI tract. While AFP expression in adult cells is low, it is aberrantly expressed in adult liver cancer cells (1,2). The tumor suppressor gene p53 and b-catenin are both involved in the regulation of AFP expression. In normal adult cells, p53 binds to the repressor region of the AFP gene, thereby blocking transcription. Mutations in both p53 and b-catenin are associated with aberrant expression of AFP. Elevated serum levels are predictive of hepatocellular carcinoma (3).
Product Categories/Family for anti-AFP antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
68,678 Da
NCBI Official Full Name
alpha-fetoprotein
NCBI Official Synonym Full Names
alpha-fetoprotein
NCBI Official Symbol
AFP
NCBI Official Synonym Symbols
AFPD; FETA; HPAFP
NCBI Protein Information
alpha-fetoprotein
UniProt Protein Name
Alpha-fetoprotein
UniProt Gene Name
AFP
UniProt Synonym Gene Names
HPAFP
UniProt Entry Name
FETA_HUMAN
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Product Notes
The AFP afp (Catalog #AAA302256) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AFP Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's AFP can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the AFP afp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AFP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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