ICC (Immunocytochemistry)
(Immunocytochemistry of AIF in K562 cells with AIF antibody at 5 μg/mL.)
Rabbit AIF Polyclonal Antibody | anti-CNKSR1 antibody
AIF Antibody
Gene Names
CNKSR1; CNK; CNK1
Reactivity
Human, Mouse, Rat
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
AIF Antibody is DEAE purified.
Synonyms
AIF, Antibody; AIF Antibody; AIF; CNK; KSR; CNK1; Connector enhancer of kinase suppressor of ras 1; CNK homolog protein 1; Connector enhancer of KSR 1; connector enhancer of kinase suppressor of Ras 1; anti-CNKSR1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
AIF Antibody is DEAE purified.
Form/Format
Liquid
Sequence Length
720
Applicable Applications for anti-CNKSR1 antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
AIF antibody was raised against a 14 amino acid peptide near the carboxy terminus of human AIF.
Buffer
AIF Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
AIF antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of AIF in K562 cells with AIF antibody at 5 μg/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of AIF in K562 cells with AIF antibody at 5 μg/mL.)
WB (Western Blot)
(Western blot analysis of AIF in K562 with AIF antibody at (A) 0.5, (B) 1, and (C) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of AIF in K562 with AIF antibody at (A) 0.5, (B) 1, and (C) 2 μg/mL.)
Related Product Information for anti-CNKSR1 antibody
AIF Antibody: Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins. A novel gene, the product of which causes chromatin condensation and DNA fragmentation, was recently identified, cloned, and designated apoptosis inducing factor (AIF). Like the critical molecules, cytochrome c and caspase-9, in apoptosis, AIF localizes in mitochondria. AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. AIF induces chromatin condensation and DNA fragmentation, which are the hallmarks of apoptosis, of the isolated nucleus and the nucleus in live cells by microinjection. AIF is highly conserved between human and mouse and widely expressed.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
67 kDa
NCBI Official Full Name
Connector enhancer of kinase suppressor of ras 1
NCBI Official Synonym Full Names
connector enhancer of kinase suppressor of Ras 1
NCBI Official Symbol
CNKSR1
NCBI Official Synonym Symbols
CNK; CNK1
NCBI Protein Information
connector enhancer of kinase suppressor of ras 1; CNK homolog protein 1; connector enhancer of KSR 1
UniProt Protein Name
Connector enhancer of kinase suppressor of ras 1
UniProt Gene Name
CNKSR1
UniProt Synonym Gene Names
CNK1; Connector enhancer of KSR 1; CNK1; hCNK1
UniProt Entry Name
CNKR1_HUMAN
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Product Notes
The CNKSR1 cnksr1 (Catalog #AAA39244) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AIF Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's AIF can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the CNKSR1 cnksr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AIF, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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