Rabbit AIFM1 Polyclonal Antibody | anti-AIFM1 antibody

AIFM1 Polyclonal Antibody

Cat. Num. AAA174460

• Gene Names: AIFM1; AIF; CMT2D; CMTX4; COWCK; DFNX5; NADMR; NAMSD; PDCD8; COXPD6
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry
• Purity: Affinity Purification
• Synonyms: AIFM1, Antibody; AIFM1 Polyclonal Antibody; AIFM1; Apoptosis inducing factor 1; mitochondrial; Apoptosis inducing factor; mitochondrion associated; 1; Apoptosis-inducing factor 1; CMTX4; COWCK; COXPD6; Harlequin; Hq; mAIF; MGC111425; MGC5706; Neuropathy; axonal motor-sensory; with deafness and mental retardation; neuropathy; axonal; motor-sensory with deafness and mental retardation (Cowchock syndrome); PDCD 8; PDCD8; Programmed cell death 8 (apoptosis inducing factor); Programmed cell death 8; Programmed cell death 8 isoform 1; Programmed cell death 8 isoform 2; Programmed cell death 8 isoform 3; Programmed cell death protein 8; Programmed cell death protein 8 mitochondrial; Programmed cell death protein 8 mitochondrial precursor; Striatal apoptosis inducing factor; anti-AIFM1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity Purification
• Form/Format: PBS with 0.02% sodium azide, 100 mug/ml BSA and 50% glycerol.
• Concentration: 0.98 mg/mL (varies by lot)
• Sequence Length: 326

• Applicable Applications for anti-AIFM1 antibody: IHC (Immunohistochemistry)
• Immunogen: KLH conjugated synthetic peptide corresponding to Mouse AIF
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

IHC (Immunohistochemisry)

(Immunohistochemistry analysis of paraffin-embedded Rat spleen using AIFM1 Polyclonal Antibody at dilution of 1:400.)

IHC (Immunohiostchemistry)

(Immunohistochemistry analysis of paraffin-embedded mouse spleen using AIFM1 Polyclonal Antibody at dilution of 1:400.)

IHC (Immunohistochemistry)

(Immunohistochemistry analysis of paraffin-embedded human Tonsil using AIFM1 Polyclonal Antibody at dilution of 1:400.)

Related Product Information for anti-AIFM1 antibody

This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.

Product Categories/Family for anti-AIFM1 antibody

Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Metabolism

NCBI and Uniprot Product Information

• NCBI GI #: 923424571
• NCBI GeneID: 9131
• NCBI Accession #: NP_001124318.2
• NCBI GenBank Nucleotide #: NM_001130846.3
• UniProt Accession #: O95831; Q1L6K4; Q1L6K6; Q2QKE4; Q5JUZ7; Q6I9X6; Q9Y3I3; Q9Y3I4; A4QPB4; B1ALN1; B2RB08; D3DTE9
• Molecular Weight: 35,638 Da
• NCBI Official Full Name: apoptosis-inducing factor 1, mitochondrial isoform AIFsh
• NCBI Official Synonym Full Names: apoptosis inducing factor mitochondria associated 1
• NCBI Official Symbol: AIFM1
• NCBI Official Synonym Symbols: AIF; CMT2D; CMTX4; COWCK; DFNX5; NADMR; NAMSD; PDCD8; COXPD6
• NCBI Protein Information: apoptosis-inducing factor 1, mitochondrial
• UniProt Protein Name: Apoptosis-inducing factor 1, mitochondrial
• UniProt Gene Name: AIFM1
• UniProt Synonym Gene Names: AIF; PDCD8