IHC (Immunohiostchemistry)
(Detection of human AKAP8/AKAP95 by immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-AKAP8/AKAP95 (Cat. No. AAA213872) used at a dilution of 1:500. Detection: DAB)
Rabbit anti-Human, Mouse AKAP8/AKAP95 Polyclonal Antibody | anti-AKAP8/AKAP95 antibody
Rabbit anti-AKAP8/AKAP95 IHC Antibody, Affinity Purified
Gene Names
AKAP8; AKAP-8; AKAP95; AKAP 95; AKAP-95
Reactivity
Human, Mouse
Applications
Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
AKAP8/AKAP95, Antibody; Rabbit anti-AKAP8/AKAP95 IHC Antibody, Affinity Purified; AKAP-8; A-kinase anchor protein, 95kDa; A-kinase anchor protein 95 kDa; A-kinase anchor protein 8; AKAP-95; AKAP 95; A kinase (PRKA) anchor protein 8; AKAP95; A-kinase anchoring protein 8; anti-AKAP8/AKAP95 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Concentration
100ug/ml (varies by lot)
Applicable Applications for anti-AKAP8/AKAP95 antibody
IHC (Immunohistochemistry)
Predicted Reactivity
Bovine, Gorilla, Chimpanzee
Immunogen
Between 642 and C-terminus
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Shelf Life: 1 year from date of receipt
IHC (Immunohiostchemistry)
(Detection of human AKAP8/AKAP95 by immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-AKAP8/AKAP95 (Cat. No. AAA213872) used at a dilution of 1:500. Detection: DAB)
IHC (Immunohiostchemistry)
(Detection of human AKAP8/AKAP95 by immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-AKAP8/AKAP95 (Cat. No. AAA213872) used at a dilution of 1:500. Detection: DAB)
IHC (Immunohistochemistry)
(Detection of mouse AKAP8/AKAP95 by immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-AKAP8/AKAP95 (Cat. No. AAA213872) used at a dilution of 1:100. Detection: DAB)
IHC (Immunohistochemistry)
(Detection of mouse AKAP8/AKAP95 by immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-AKAP8/AKAP95 (Cat. No. AAA213872) used at a dilution of 1:100. Detection: DAB)
Related Product Information for anti-AKAP8/AKAP95 antibody
AKAP8/AKAP95 has been characterized as a 95 kDa protein kinase A (PKA)-anchoring protein and regulatory subunit of PKA that functions to recruit the condensin complex for chromosome condensation during mitosis. A role in DNA replication has also been demonstrated through its interaction with the pre-replication complex component, MCM2 (mini-chromosome maintenance 2). Inhibition of AKAP8/AKAP95 association with MCM2 inhibits replication initiation and elongation in vitro. AKAP8/AKAP95 has also been shown to be involved in apoptosis. KAP8/AKAP95 associates with caspase 3 and serves as a carrier to transport caspase 3 from the cytoplasm to the nucleus to induce morphological changes in the nucleus.
Product Categories/Family for anti-AKAP8/AKAP95 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
76,108 Da
NCBI Official Full Name
A-kinase anchor protein 8
NCBI Official Synonym Full Names
A kinase (PRKA) anchor protein 8
NCBI Official Symbol
AKAP8
NCBI Official Synonym Symbols
AKAP-8; AKAP95; AKAP 95; AKAP-95
NCBI Protein Information
A-kinase anchor protein 8; A-kinase anchor protein, 95kDa
UniProt Protein Name
A-kinase anchor protein 8
UniProt Gene Name
AKAP8
UniProt Synonym Gene Names
AKAP95; AKAP-8; AKAP 95
UniProt Entry Name
AKAP8_HUMAN
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Product Notes
The AKAP8/AKAP95 akap8 (Catalog #AAA213872) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-AKAP8/AKAP95 IHC Antibody, Affinity Purified reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's AKAP8/AKAP95 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the AKAP8/AKAP95 akap8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AKAP8/AKAP95, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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