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product-image-AAA213917_IHC11.jpg IHC (Immunohistochemisry) (Detection of human AKAP8L/HA95 by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-AKAP8L/HA95 (Cat. No. AAA213917) used at a dilution of 1:100. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed IHC Antibody Hilyte Plus 555 used at a dilution of 1:100.)

Rabbit anti-Human AKAP8L/HA95 Polyclonal Antibody | anti-AKAP8L/HA95 antibody

Rabbit anti-AKAP8L/HA95 IHC Antibody, Affinity Purified

Gene Names
AKAP8L; HA95; HAP95; NAKAP; NAKAP95
Reactivity
Human
Applications
Immunohistochemistry, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
AKAP8L/HA95, Antibody; Rabbit anti-AKAP8L/HA95 IHC Antibody, Affinity Purified; Helicase A-binding protein 95; testis tissue sperm-binding protein Li 90mP; Neighbor of A-kinase-anchoring protein 95; neighbor of A-kinase anchoring protein 95; neighbor of AKAP95; NAKAP95; NAKAP; homologous to AKAP95 protein; HAP95; HA95; A-kinase anchor protein 8-like; AKAP8-like protein; A kinase (PRKA) anchor protein 8-like; helicase A-binding protein 95 kDa; A-kinase anchoring protein 8 like; anti-AKAP8L/HA95 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Concentration
200ug/ml (varies by lot)
Applicable Applications for anti-AKAP8L/HA95 antibody
IHC (Immunohistochemistry), IHC (Immunohistochemistry)
Predicted Reactivity
Gorilla, Chimpanzee, Naked mole rat, Chinese hamster, Northern white-cheeked gibbon
Immunogen
Between 596 and C-terminus
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt

IHC (Immunohistochemisry)

(Detection of human AKAP8L/HA95 by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-AKAP8L/HA95 (Cat. No. AAA213917) used at a dilution of 1:100. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed IHC Antibody Hilyte Plus 555 used at a dilution of 1:100.)

product-image-AAA213917_IHC11.jpg IHC (Immunohistochemisry) (Detection of human AKAP8L/HA95 by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-AKAP8L/HA95 (Cat. No. AAA213917) used at a dilution of 1:100. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed IHC Antibody Hilyte Plus 555 used at a dilution of 1:100.)

IHC (Immunohiostchemistry)

(Detection of human AKAP8L/HA95 by immunohistochemistry. Sample: FFPE section of human pancreatic islet cell tumor. Antibody: Affinity purified rabbit anti-AKAP8L/HA95 (Cat. No. AAA213917) used at a dilution of 1:250. Detection: DAB)

product-image-AAA213917_IHC13.jpg IHC (Immunohiostchemistry) (Detection of human AKAP8L/HA95 by immunohistochemistry. Sample: FFPE section of human pancreatic islet cell tumor. Antibody: Affinity purified rabbit anti-AKAP8L/HA95 (Cat. No. AAA213917) used at a dilution of 1:250. Detection: DAB)

IHC (Immunohistochemistry)

(Detection of human AKAP8L/HA95 by immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-AKAP8L/HA95 (Cat. No. AAA213917) used at a dilution of 1:250. Detection: DAB)

product-image-AAA213917_IHC15.jpg IHC (Immunohistochemistry) (Detection of human AKAP8L/HA95 by immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-AKAP8L/HA95 (Cat. No. AAA213917) used at a dilution of 1:250. Detection: DAB)
Related Product Information for anti-AKAP8L/HA95 antibody
AKAP8L/HA95 is a PKA anchoring protein that is localized to the nuclear envelope and associates with chromatin upon nuclear envelope breakdown during mitosis. AKAP8L/HA95 has been found to play an important role in the initiation of DNA replication and may function as a scaffold for proteins such as MCM2 and LAP2beta. Additionally, AKAP8L/HA95 has been shown to co-locate with the PKA C subunit in splicing factor compartments and is involved in the regulation of pre-mRNA splicing. Further support for a scaffolding and splicing role in the nucleus comes from the observation that AKAP8L/HA95 colocalizes with HypA, a splicing-like factor, and through this association may function as a docking site for the nuclear accumulation of Huntington protein as seen in Huntington's disease.
Product Categories/Family for anti-AKAP8L/HA95 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
71649
NCBI Official Full Name
A-kinase anchor protein 8-like
NCBI Official Synonym Full Names
A kinase (PRKA) anchor protein 8-like
NCBI Official Symbol
AKAP8L
NCBI Official Synonym Symbols
HA95; HAP95; NAKAP; NAKAP95
NCBI Protein Information
A-kinase anchor protein 8-like
UniProt Protein Name
A-kinase anchor protein 8-like
UniProt Gene Name
AKAP8L
UniProt Synonym Gene Names
NAKAP; NAKAP95; AKAP8-like protein; HAP95; HA95; Neighbor of AKAP95
UniProt Entry Name
AKP8L_HUMAN

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Product Notes

The AKAP8L/HA95 akap8l (Catalog #AAA213917) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-AKAP8L/HA95 IHC Antibody, Affinity Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AKAP8L/HA95 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the AKAP8L/HA95 akap8l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AKAP8L/HA95, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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