IHC (Immunohiostchemistry)
(Ankyrin 1 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Alveolar cells (arrows) in Human Lung. Magnification is at 400X)
Rabbit Ankyrin 1 Polyclonal Antibody | anti-ANK1 antibody
Ankyrin 1 antibody
Gene Names
ANK1; ANK; SPH1; SPH2
Applications
Immunohistochemistry, Western Blot
Purity
Total IgG Protein A purified
Synonyms
Ankyrin 1, Antibody; Ankyrin 1 antibody; Polyclonal Ankyrin 1; Anti-Ankyrin 1; SPH2; ANK1; SPH1; Ankyrin 1 Erythrocytic; anti-ANK1 antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
Ankyrin 1 antibody was raised against the C terminal of ANK1
Purity/Purification
Total IgG Protein A purified
Form/Format
Lyophilized powder. Add 100ul distilled water for a 1mg/ml concentration of ANK1 antibody in PBS
Concentration
1 mg/ml (varies by lot)
Sequence Length
1881
Applicable Applications for anti-ANK1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Biological Significance
Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Ankyrin 1, the prototype of this family, was first discovered in the erythrocytes, but since has also been found in brain and muscles. Mutations in erythrocytic ankyrin 1 have been associated in approximately half of all patients with hereditary spherocytosis. Complex patterns of alternative splicing in the regulatory domain, giving rise to different isoforms of ankyrin 1 have been described, however, the precise functions of the various isoforms are not known.
Cross-Reactivity
Human, Mouse, Rat, Dog
Immunogen
Ankyrin 1 antibody was raised using the C terminal of ANK1 corresponding to a region with amino acids VVRQIDLSSADAAQEHEEVELRGSGLQPDLIEGRKGAQIVKRASLKRGKQ
Preparation and Storage
Store at 2-8 degree C for short periods. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Ankyrin 1 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Alveolar cells (arrows) in Human Lung. Magnification is at 400X)
IHC (Immunohiostchemistry)
(Ankyrin 1 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Alveolar cells (arrows) in Human Lung. Magnification is at 400X)
WB (Western Blot)
(Ankyrin 1 antibody (AAA224460) used at 1.25 ug/ml to detect target protein.)
WB (Western Blot)
(Ankyrin 1 antibody (AAA224460) used at 1.25 ug/ml to detect target protein.)
Related Product Information for anti-ANK1 antibody
Rabbit polyclonal Ankyrin 1 antibody raised against the C terminal of ANK1
Product Categories/Family for anti-ANK1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
17 kDa (MW of target protein)
NCBI Official Full Name
ankyrin-1 isoform 1
NCBI Official Synonym Full Names
ankyrin 1, erythrocytic
NCBI Official Symbol
ANK1
NCBI Official Synonym Symbols
ANK; SPH1; SPH2
NCBI Protein Information
ankyrin-1
UniProt Protein Name
Ankyrin-1
UniProt Gene Name
ANK1
UniProt Synonym Gene Names
ANK; ANK-1
UniProt Entry Name
ANK1_HUMAN
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Product Notes
The ANK1 ank1 (Catalog #AAA224460) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Ankyrin 1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the ANK1 ank1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ankyrin 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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