IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using AAA304254 at dilution 1/40.)
Rabbit anti-Human, Mouse ANO1 Polyclonal Antibody | anti-ANO1 antibody
ANO1 Antibody
Gene Names
ANO1; DOG1; TAOS2; ORAOV2; TMEM16A
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
Antigen affinity purification.
Synonyms
ANO1, Antibody; ANO1 Antibody; DOG1; TAOS2; ORAOV2; TMEM16A; anti-ANO1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total ANO1 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
2 mg/ml (varies by lot)
Sequence Length
986
Applicable Applications for anti-ANO1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to a region derived from internal residues of human anoctamin 1, calcium activated chloride channel
Target Name
ANO1
Preparation and Storage
Store at -20°C
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using AAA304254 at dilution 1/40.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using AAA304254 at dilution 1/40.)
Application Data
(Gel: 6%SDS-PAGELysates (from left to right): Human fetal brain tissueAmount of lysate: 40ug per lanePrimary antibody: 1/250 dilutionSecondary antibody dilution: 1/8000Exposure time: 3 minutes)
Application Data
(Gel: 6%SDS-PAGELysates (from left to right): Human fetal brain tissueAmount of lysate: 40ug per lanePrimary antibody: 1/250 dilutionSecondary antibody dilution: 1/8000Exposure time: 3 minutes)
Related Product Information for anti-ANO1 antibody
TMEM16A, also known as DOG1, ORAOV2, TAOS2 or ANO1 (anoctamin 1), is a 986 amino acid multi-pass membrane protein that localizes to both the cell membrane and the cytoplasm and belongs to the anoctamin family. Expressed in a variety of tissues with highest expression in skeletal muscle and liver, TMEM16A functions as a calcium-activated chloride channel that is required for normal tracheal development. Human TMEM16A shares 90% sequence identity with its mouse counterpart, suggesting a conserved role between species. TMEM16A is present in breast, pancreatic, gastric, and uterine cancers, as well as in neck, ovarian and parathyroid tumors, suggesting a role for TMEM16A in carcinogenesis. Three isoforms of TMEM16A exist due to alternative splicing events.
Product Categories/Family for anti-ANO1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
SDS-PAGE MW: 114kd
NCBI Official Full Name
anoctamin-1
NCBI Official Synonym Full Names
anoctamin 1, calcium activated chloride channel
NCBI Official Symbol
ANO1
NCBI Official Synonym Symbols
DOG1; TAOS2; ORAOV2; TMEM16A
NCBI Protein Information
anoctamin-1
UniProt Protein Name
Anoctamin-1
UniProt Gene Name
ANO1
UniProt Synonym Gene Names
DOG1; ORAOV2; TAOS2; TMEM16A
UniProt Entry Name
ANO1_HUMAN
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Product Notes
The ANO1 ano1 (Catalog #AAA304254) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ANO1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ANO1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the ANO1 ano1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ANO1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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