Rabbit anti-Human ASAH3 Polyclonal Antibody | anti-ASAH3 antibody
ASAH3 Polyclonal Antibody
Gene Names
ACER1; ASAH3; ALKCDase1
Reactivity
Human
Applications
Western Blot
Synonyms
ASAH3, Antibody; ASAH3 Polyclonal Antibody; ACER1; ASAH3; Alkaline ceramidase 1; AlkCDase 1; Alkaline CDase 1; Acylsphingosine deacylase 3; N-acylsphingosine amidohydrolase 3; anti-ASAH3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Applicable Applications for anti-ASAH3 antibody
WB (Western Blot)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Related Product Information for anti-ASAH3 antibody
Endoplasmic reticulum ceramidase that catalyzes the hydrolysis of ceramides into sphingosine and free fatty acids at alkaline pH (PubMed:20207939, PubMed:20628055). Ceramides, sphingosine, and its phosphorylated form sphingosine-1- phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation (PubMed:20207939). May also hydrolyze dihydroceramides to produce dihydrosphingosine (PubMed:20628055). ACER1 is a skin-specific ceramidase that regulates the levels of ceramides, sphingosine and sphingosine-1-phosphate in the epidermis, mediates the calcium-induced differentiation of epidermal keratinocytes and more generally plays an important role in skin homeostasis (PubMed:17713573).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
31,095 Da
NCBI Official Full Name
alkaline ceramidase 1
NCBI Official Synonym Full Names
alkaline ceramidase 1
NCBI Official Symbol
ACER1
NCBI Official Synonym Symbols
ASAH3; ALKCDase1
NCBI Protein Information
alkaline ceramidase 1
UniProt Protein Name
Alkaline ceramidase 1
UniProt Gene Name
ACER1
UniProt Synonym Gene Names
ASAH3; AlkCDase 1; Alkaline CDase 1
UniProt Entry Name
ACER1_HUMAN
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Product Notes
The ASAH3 acer1 (Catalog #AAA296414) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ASAH3 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ASAH3 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the ASAH3 acer1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ASAH3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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