IHC (Immunohiostchemistry)
(Anti- Ataxin 1 Picoband antibody, AAA46493, IHC(P)IHC(P): Human Lung Cancer Tissue)
anti-Human Ataxin 1 Polyclonal Antibody | anti-ATXN1 antibody
Anti-Ataxin 1 Antibody
Gene Names
ATXN1; ATX1; SCA1; D6S504E
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen Affinity Purified
Synonyms
Ataxin 1, Antibody; Anti-Ataxin 1 Antibody; Ataxin-1; ATX1; ATX1_HUMAN; Atxn1; D6S504E; OTTHUMP00000016065; SCA1; Spinocerebellar ataxia type 1 protein antibody; ataxin 1; anti-ATXN1 antibody
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Immunogen Affinity Purified
Form/Format
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
815
Applicable Applications for anti-ATXN1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Ataxin 1 (778-808aa ESRKLEKSEDEPPLTLPKPSLIPQEVKICIE), different from the related mouse and rat sequences by one amino acid.
Ig Type
Rabbit IgG
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(Anti- Ataxin 1 Picoband antibody, AAA46493, IHC(P)IHC(P): Human Lung Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti- Ataxin 1 Picoband antibody, AAA46493, IHC(P)IHC(P): Human Lung Cancer Tissue)
WB (Western Blot)
(Anti- Ataxin 1 Picoband antibody, AAA46493, Western blottingAll lanes: Anti Ataxin 1 (AAA46493) at 0.5ug/mlLane 1: MCF-7 Whole Cell Lysate at 40ugLane 2: COLO320 Whole Cell Lysate at 40ugLane 3: PANC Whole Cell Lysate at 40ugPredicted bind size: 87KDObserved bind size: 87KD)
WB (Western Blot)
(Anti- Ataxin 1 Picoband antibody, AAA46493, Western blottingAll lanes: Anti Ataxin 1 (AAA46493) at 0.5ug/mlLane 1: MCF-7 Whole Cell Lysate at 40ugLane 2: COLO320 Whole Cell Lysate at 40ugLane 3: PANC Whole Cell Lysate at 40ugPredicted bind size: 87KDObserved bind size: 87KD)
Related Product Information for anti-ATXN1 antibody
Description: Rabbit IgG polyclonal antibody for Ataxin-1(ATXN1) detection. Tested with WB, IHC-P in Human.
Background: Ataxin-1 is a protein that in humans is encoded by the ATXN1 gene. The ATXN1 gene had been mapped to 6p23 by in situ hybridization. Ataxin-1 (ATXN1), a causative factor for spinocerebellar ataxia type 1 (SCA1), and the related Brother of ATXN1 (BOAT1) are human proteins involved in transcriptional repression. ATXN1 and BOAT1 might participate in several Notch-controlled developmental and pathological processes.
Background: Ataxin-1 is a protein that in humans is encoded by the ATXN1 gene. The ATXN1 gene had been mapped to 6p23 by in situ hybridization. Ataxin-1 (ATXN1), a causative factor for spinocerebellar ataxia type 1 (SCA1), and the related Brother of ATXN1 (BOAT1) are human proteins involved in transcriptional repression. ATXN1 and BOAT1 might participate in several Notch-controlled developmental and pathological processes.
References
1. "Entrez Gene: ATXN1 ataxin 1" 2. Tong, X., Gui, H., Jin, F., Heck, B. W., Lin, P., Ma, J., Fondell, J. D., Tsai, C.-C. Ataxin-1 and brother of ataxin-1 are components of the Notch signalling pathway. EMBO Rep. 12: 428-435, 2011. 3. Volz A, Fonatsch C, Ziegler A (Jun 1992). "Regional mapping of the gene for autosomal dominant spinocerebellar ataxia (SCA1) by localizing the closely linked D6S89 locus to 6p24.2----p23.05". Cytogenet Cell Genet 60 (1): 37-9. 4. Volz, A., Boyle, J. M., Cann, H. M., Cottingham, R. W., Orr, H. T., Ziegler, A. Report of the second international workshop on human chromosome 6. Genomics 21: 464, 1994.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
86,923 Da
NCBI Official Full Name
ataxin-1
NCBI Official Synonym Full Names
ataxin 1
NCBI Official Symbol
ATXN1
NCBI Official Synonym Symbols
ATX1; SCA1; D6S504E
NCBI Protein Information
ataxin-1
UniProt Protein Name
Ataxin-1
UniProt Gene Name
ATXN1
UniProt Synonym Gene Names
ATX1; SCA1
UniProt Entry Name
ATX1_HUMAN
Similar Products
Product Notes
The ATXN1 atxn1 (Catalog #AAA46493) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-Ataxin 1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Ataxin 1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the ATXN1 atxn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ataxin 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.