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WB (Western Blot)
(Western blot of ATF6 in MCF7 cell lysate with ATF6 antibody at (A) 0.5 and (B) 1 ug/ml.)
Rabbit anti-Human, Mouse ATF6 Polyclonal Antibody | anti-ATF6 antibody
Rabbit Polyclonal to Human ATF6
Gene Names
ATF6; ATF6A
Reactivity
Human, Mouse
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
ATF6, Antibody; Rabbit Polyclonal to Human ATF6; Anti-ATF6 Antibody (C-Terminus) IHC-plus; ATF6; ATF6-alpha; ATF6A; Human ATF6; anti-ATF6 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
16 amino acid peptide from near the carboxy terminus of human ATF6
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.02% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
670
Applicable Applications for anti-ATF6 antibody
WB (Western Blot), ICC (Immunocytochemistry), IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
Synthetic peptide from human ATF6.
Immunogen Type
Synthetic peptide
Immunogen
ATF6 antibody was raised against synthetic peptide from human ATF6.
Antigen Modification
C-Terminus
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
WB (Western Blot)
(Western blot of ATF6 in MCF7 cell lysate with ATF6 antibody at (A) 0.5 and (B) 1 ug/ml.)
WB (Western Blot)
(Western blot of ATF6 in MCF7 cell lysate with ATF6 antibody at (A) 0.5 and (B) 1 ug/ml.)
ICC (Immunocytochemistry)
(Immunocytochemical staining of MCF7 cells using ATF6 antibody at 10 ug/ml.)
ICC (Immunocytochemistry)
(Immunocytochemical staining of MCF7 cells using ATF6 antibody at 10 ug/ml.)
IF (Immunofluorescence)
(Immunofluorescence of ATF6 in MCF7 cells with ATF6 antibody at 10 ug/ml.)
IF (Immunofluorescence)
(Immunofluorescence of ATF6 in MCF7 cells with ATF6 antibody at 10 ug/ml.)
IHC (Immunohistochemistry)
(Anti-ATF6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
IHC (Immunohistochemistry)
(Anti-ATF6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Related Product Information for anti-ATF6 antibody
Activating Transcription Factor 6 (ATF6) is a type II transmembrane glycoprotein located on the ER membrane. In response to ER stress ATF6 is cleaved and the N-terminus including the leucine zipper (which faces the cytosol) moves to the nucleus. Once in the nucleus ATF6 binds to the ER stress response elements in ER stress genes. Site-1 and site-2 protease enzymes that process sterol regulatory binding proteins in response to cholesterol derivation cleave ATF6.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
74,585 Da
NCBI Official Full Name
cyclic AMP-dependent transcription factor ATF-6 alpha
NCBI Official Synonym Full Names
activating transcription factor 6
NCBI Official Symbol
ATF6
NCBI Official Synonym Symbols
ATF6A
NCBI Protein Information
cyclic AMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 alpha
UniProt Protein Name
Cyclic AMP-dependent transcription factor ATF-6 alpha
UniProt Gene Name
ATF6
UniProt Synonym Gene Names
cAMP-dependent transcription factor ATF-6 alpha; ATF6-alpha
UniProt Entry Name
ATF6A_HUMAN
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Product Notes
The ATF6 atf6 (Catalog #AAA50886) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human ATF6 reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ATF6 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), ICC (Immunocytochemistry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the ATF6 atf6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATF6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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