Rabbit anti-Human, Mouse ATG4C Polyclonal Antibody | anti-ATG4C antibody

ATG4C Antibody

Cat. Num. AAA303307

• Gene Names: ATG4C; APG4C; AUTL1; AUTL3; APG4-C
• Reactivity: Human, Mouse
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: ATG4C, Antibody; ATG4C Antibody; APG4 autophagy 4 homolog C; APG4-C; APG4C; AUT-like 3 cysteine endopeptidase; AUTL1; anti-ATG4C antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total ATG4C protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 458

• Applicable Applications for anti-ATG4C antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen Type: Peptide
• Immunogen Description: Synthesized peptide derived from internal of human ATG4C.
• Target Name: ATG4C
• Preparation and Storage: Store at -20 degree C

IF (Immunofluorescence)

(Immunofluorescence analysis of HuvEc cells, using ATG4C antibody.)

IHC (Immunohiostchemistry)

(Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using ATG4C antibody.)

WB (Western Blot)

(Western blot analysis of extracts from K562 cells and COS7 cells, using ATG4C antibody.)

Related Product Information for anti-ATG4C antibody

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation By similarity. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.Marino G., J. Biol. Chem. 278:3671-3678(2003).Chen J.M., Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.Ota T., Nat. Genet. 36:40-45(2004).

Product Categories/Family for anti-ATG4C antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 30410844
• NCBI GeneID: 84938
• NCBI Accession #: NP_116241.2
• NCBI GenBank Nucleotide #: NM_032852.3
• UniProt Accession #: Q96DT6; Q96K04; A6NLR8; D3DQ58
• Molecular Weight: 52,497 Da
• NCBI Official Full Name: cysteine protease ATG4C
• NCBI Official Synonym Full Names: autophagy related 4C, cysteine peptidase
• NCBI Official Symbol: ATG4C
• NCBI Official Synonym Symbols: APG4C; AUTL1; AUTL3; APG4-C
• NCBI Protein Information: cysteine protease ATG4C
• UniProt Protein Name: Cysteine protease ATG4C
• UniProt Gene Name: ATG4C
• UniProt Synonym Gene Names: APG4C; AUTL1; AUTL3
• UniProt Entry Name: ATG4C_HUMAN