Host
Rabbit
Clonality
Polyclonal
Specificity
This antibody recognizes human and rat Atg4C
Form/Format
Peptide affinity-purified antibody in PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.
Concentration
1mg/ml (varies by lot)
Sequence Length
458
Applicable Applications for anti-Atg4C antibody
IB (Immunoblot)
Antigen
Synthetic peptide corresponding to amino acids at the N-terminus of human Atg4C.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
Related Product Information for anti-Atg4C antibody
Autophagy is a catabolic process that results in the degradation of bulk cytoplasmic contents within autophagosomes and lysosomes. Recent studies demonstrated that Atg4D is a substrate for caspase-3 during apoptosis. Truncated Atg4D has increased priming and delipidation effects on the Atg8 paralogue GABARAP-L1 in vitro and induces cell death when overexpressed in human cells. In addition, Atg4D-mediated apoptosis is facilitated by a putative C-terminal BH3 domain and is preceded by recruitment of Atg4D to mitochondria, suggesting that Atg4D plays an important role at the interface between autophagy and apoptosis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52,497 Da
NCBI Official Full Name
cysteine protease ATG4C
NCBI Official Synonym Full Names
autophagy related 4C cysteine peptidase
NCBI Official Symbol
ATG4C
NCBI Official Synonym Symbols
APG4C; AUTL1; AUTL3; APG4-C
NCBI Protein Information
cysteine protease ATG4C
UniProt Protein Name
Cysteine protease ATG4C
UniProt Gene Name
ATG4C
UniProt Synonym Gene Names
APG4C; AUTL1; AUTL3
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Product Notes
The Atg4C atg4c (Catalog #AAA47778) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Atg4C can be used in a range of immunoassay formats including, but not limited to, IB (Immunoblot). Researchers should empirically determine the suitability of the Atg4C atg4c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Atg4C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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