IF (Immunofluorescence)
(Immunofluorescence of ATM in Human Lymph Node cells with ATM antibody at 10 μg/mL.)
Rabbit anti-Human ATM Polyclonal Antibody | anti-ATM antibody
ATM Antibody
Gene Names
ATM; AT1; ATA; ATC; ATD; ATE; ATDC; TEL1; TELO1
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
ATM Antibody is affinity chromatography purified via peptide column.
Synonyms
ATM, Antibody; ATM Antibody; ATM; AT1; ATA; ATC; ATD; ATE; ATDC; TEL1; TELO1; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated; ataxia telangiectasia mutated; anti-ATM antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
ATM Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
3056
Applicable Applications for anti-ATM antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
ATM antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human ATM.
Buffer
ATM Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
ATM antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of ATM in Human Lymph Node cells with ATM antibody at 10 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of ATM in Human Lymph Node cells with ATM antibody at 10 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of ATM in human lymph node tissue with ATM antibody at 2.5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of ATM in human lymph node tissue with ATM antibody at 2.5 μg/mL.)
WB (Western Blot)
(Western blot analysis of ATM in Daudi whole cell lysate with ATM antibody at (A) 1 and (B) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of ATM in Daudi whole cell lysate with ATM antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-ATM antibody
ATM Antibody: DNA double strand breaks represent a major threat to an organism's genome. Eukaryotic cells have developed mechanisms that sense the presence this damage and initiate suitable responses that can include DNA repair, cell cycle delay, and programmed cell death. The ATM (mutated in Ataxia-Telangiectasia) protein kinase is activated following the formation of DNA double strand breaks, phosphorylating p53 and another kinase CHK2. This initiates a signaling cascade leading to the phosphorylation and inhibition of Cdc25, ultimately preventing cell cycle progression. In some cell types, such as the hemapoietic system, this leads to apoptosis instead of cell cycle arrest. Multiple isoforms of ATM are known to exist.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
350,687 Da
NCBI Official Full Name
ATM
NCBI Official Synonym Full Names
ATM serine/threonine kinase
NCBI Official Symbol
ATM
NCBI Official Synonym Symbols
AT1; ATA; ATC; ATD; ATE; ATDC; TEL1; TELO1
NCBI Protein Information
serine-protein kinase ATM; AT mutated; A-T mutated; ataxia telangiectasia mutated; TEL1, telomere maintenance 1, homolog
UniProt Protein Name
Serine-protein kinase ATM
UniProt Gene Name
ATM
UniProt Synonym Gene Names
A-T mutated
UniProt Entry Name
ATM_HUMAN
Similar Products
Product Notes
The ATM atm (Catalog #AAA39431) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ATM Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ATM can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the ATM atm for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATM, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.