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product-image-AAA302279_IF10.jpg IF (Immunofluorescence) (Immunofluorescence analysis of HeLa cell using ATXN3 antibody. Blue: DAPI for nuclear staining.)

Rabbit ATXN3 Polyclonal Antibody | anti-ATXN3 antibody

ATXN3 Antibody

Gene Names
ATXN3; AT3; JOS; MJD; ATX3; MJD1; SCA3
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Antibodies were purified by affinity purification using immunogen.
Synonyms
ATXN3, Antibody; ATXN3 Antibody; ATXN3; AT3; ATX3; JOS; MJD; anti-ATXN3 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total ATXN3 protein.
Purity/Purification
Antibodies were purified by affinity purification using immunogen.
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
346
Applicable Applications for anti-ATXN3 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Recombinant Protein
Immunogen Description
Recombinant protein of human ATXN3.
Target Name
ATXN3
Preparation and Storage
Store at -20 degree C

IF (Immunofluorescence)

(Immunofluorescence analysis of HeLa cell using ATXN3 antibody. Blue: DAPI for nuclear staining.)

product-image-AAA302279_IF10.jpg IF (Immunofluorescence) (Immunofluorescence analysis of HeLa cell using ATXN3 antibody. Blue: DAPI for nuclear staining.)

IHC (Immunohistochemisry)

(Immunohistochemical analysis of paraffin-embedded rat kidney using ATXN3 antibody at dilution of 1:200 (400x lens).)

product-image-AAA302279_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemical analysis of paraffin-embedded rat kidney using ATXN3 antibody at dilution of 1:200 (400x lens).)

IHC (Immunohiostchemistry)

(Immunohistochemical analysis of paraffin-embedded human lung cancer using ATXN3 antibody at dilution of 1:200 (400x lens).)

product-image-AAA302279_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemical analysis of paraffin-embedded human lung cancer using ATXN3 antibody at dilution of 1:200 (400x lens).)

WB (Western Blot)

(Western blot analysis of MCF-7 cell lysate using ATXN3 antibody.)

product-image-AAA302279_WB15.jpg WB (Western Blot) (Western blot analysis of MCF-7 cell lysate using ATXN3 antibody.)
Related Product Information for anti-ATXN3 antibody
Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Product Categories/Family for anti-ATXN3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20,633 Da
NCBI Official Full Name
ataxin-3 isoform ad
NCBI Official Synonym Full Names
ataxin 3
NCBI Official Symbol
ATXN3
NCBI Official Synonym Symbols
AT3; JOS; MJD; ATX3; MJD1; SCA3
NCBI Protein Information
ataxin-3
UniProt Protein Name
Ataxin-3
UniProt Gene Name
ATXN3
UniProt Synonym Gene Names
ATX3; MJD; MJD1; SCA3
UniProt Entry Name
ATX3_HUMAN

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Product Notes

The ATXN3 atxn3 (Catalog #AAA302279) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ATXN3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ATXN3 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the ATXN3 atxn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATXN3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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