WB (Western Blot)
Goat ATXN3 Polyclonal Antibody | anti-ATXN3 antibody
ATXN3 Polyclonal Antibody
Gene Names
ATXN3; AT3; JOS; MJD; ATX3; MJD1; SCA3
Reactivity
Human, Rat, Mouse, Canine, Monkey proteins
Applications
Western Blot
Purity
Epitope Affinity Purified
Synonyms
ATXN3, Antibody; ATXN3 Polyclonal Antibody; Ataxin 3; Anti-ATXN3; AT3; ATX3; ataxin-3; ataxin 3 variant h; autosomal dominant ataxin 3; ataxin 3 variant m; ataxin 3 variant ref; JOS; josephin; Machado-Joseph; Machado-Joseph disease protein 1; MJD; MJD1; SCA3; spinocerebellar ataxia 3; olivopontocerebellar ataxia 3; spinocerebellar ataxia type 3 protein antibody; anti-ATXN3 antibody
Host
Goat
Reactivity
Human, Rat, Mouse, Canine, Monkey proteins
Clonality
Polyclonal
Isotype
IgG
Specificity
Detects levels of ATXN3 protein in transfected cells with GFP-ATXN3 and endogenous levels in U118, SH-SY5Y, At-T20 and hTERT cell lysates by Western blot.
Purity/Purification
Epitope Affinity Purified
Form/Format
Supplied as a 200 ul (3 mg/ml) aliquot in PBS. It does not contain preservatives. Glycerol and azide FREE.
Sequence Length
346
Applicable Applications for anti-ATXN3 antibody
WB (Western Blot)
Immunogen
Purified recombinant peptide derived from within residues 120 aa to 250 aa of human ATXN3 produced in E Coli.
Conjugation
Unconjugated
Note
Azide Free
Preparation and Storage
Store at -20 C for long term storage. Store at 2-8 C for up to one month.
The antibody solution should be gently mixed before use.
Avoid freeze/thaw cycles.
The antibody solution should be gently mixed before use.
Avoid freeze/thaw cycles.
WB (Western Blot)
WB (Western Blot)
Reactivity Data
Reactivity Data
Related Product Information for anti-ATXN3 antibody
Goat polyclonal antibody to ATXN3. This protein appears to be a component of the ubiquitin proteasome system and has deubiquitinase activity. It may also have roles in neuroprotection, protein homeostasis maintenance, transcriptional and cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. The protein contains Qn repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease also known as spinocerebellar ataxia-3, an autosomal dominant neurologic disorder.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
20,633 Da
NCBI Official Full Name
ataxin-3 isoform ad
NCBI Official Synonym Full Names
ataxin 3
NCBI Official Symbol
ATXN3
NCBI Official Synonym Symbols
AT3; JOS; MJD; ATX3; MJD1; SCA3
NCBI Protein Information
ataxin-3
UniProt Protein Name
Ataxin-3
UniProt Gene Name
ATXN3
UniProt Synonym Gene Names
ATX3; MJD; MJD1; SCA3
Similar Products
Product Notes
The ATXN3 atxn3 (Catalog #AAA63143) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The ATXN3 Polyclonal Antibody reacts with Human, Rat, Mouse, Canine, Monkey proteins and may cross-react with other species as described in the data sheet. AAA Biotech's ATXN3 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the ATXN3 atxn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATXN3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.