IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using AZI1 antibody.)
Rabbit anti-Human, Mouse AZI1 Polyclonal Antibody | anti-AZI1 antibody
AZI1 Antibody
Gene Names
CEP131; AZ1; ZA1; AZI1
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
AZI1, Antibody; AZI1 Antibody; 5-azacytidine-induced 1; centrosomal protein of 131 kDa; Cep131; pre-acrosome localization 1; anti-AZI1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total AZI1 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
1044
Applicable Applications for anti-AZI1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from internal of human AZI1.
Target Name
AZI1
Preparation and Storage
Store at -20 degree C
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using AZI1 antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using AZI1 antibody.)
WB (Western Blot)
(Western blot analysis of extracts from HUVEC cells, using AZI1 antibody.)
WB (Western Blot)
(Western blot analysis of extracts from HUVEC cells, using AZI1 antibody.)
Related Product Information for anti-AZI1 antibody
Component of centriolar satellites, which build a complex and dynamic network required to regulate cilia/flagellum formation. During normal and stress-induced ciliogenesis, its non-ubiquitinated form is rapidly displaced from centriolar satellites and recruited to centrosome/basal bodies in a p38 MAPK-dependent manner. In contrast, in proliferating cells, MIB1-mediated ubiquitination induces its sequestration within centriolar satellites, precluding untimely cilia formation initiation. Acts also as a negative regulator for the trafficking from the centriolar satellite BBSome protein complex to the cilia. Plays a role in sperm flagellar formation; may be involved in the regulation of intraflagellar transport (IFT) and/or intramanchette (IMT) trafficking, which are important for axoneme extension and/or cargo delivery to the nascent sperm tail. Required for optimal cell proliferation and cell cycle progression; may play a role in the regulation of genome stability and centriole duplication in non-ciliogenic cells.Kikuno R., DNA Res. 6:197-205(1999).Andersen J.S., Nature 426:570-574(2003).Olsen J.V., Cell 127:635-648(2006).
Product Categories/Family for anti-AZI1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
117,397 Da
NCBI Official Full Name
centrosomal protein of 131 kDa isoform b
NCBI Official Synonym Full Names
centrosomal protein 131kDa
NCBI Official Symbol
CEP131
NCBI Official Synonym Symbols
AZ1; ZA1; AZI1
NCBI Protein Information
centrosomal protein of 131 kDa
UniProt Protein Name
Centrosomal protein of 131 kDa
UniProt Gene Name
CEP131
UniProt Synonym Gene Names
AZI1; KIAA1118
UniProt Entry Name
CP131_HUMAN
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Product Notes
The AZI1 cep131 (Catalog #AAA307768) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AZI1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's AZI1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the AZI1 cep131 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AZI1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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