IF (Immunofluorescence)
(Immunofluorescence of BAD in Rat Thymus cells with BAD antibody at 10 μg/mL.)
Rabbit BAD Polyclonal Antibody | anti-BAD antibody
BAD Antibody
Gene Names
BAD; BBC2; BCL2L8
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
BAD Antibody is Ion exchange chromatography purified.
Synonyms
BAD, Antibody; BAD Antibody; BAD; BBC2; BCL2L8; BBC6; Bcl2 antagonist of cell death; Bcl-2-binding component 6; BCL2-associated agonist of cell death; anti-BAD antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
BAD Antibody is Ion exchange chromatography purified.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
168
Applicable Applications for anti-BAD antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
Bad antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of human Bad.
Buffer
BAD Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
BAD antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of BAD in Rat Thymus cells with BAD antibody at 10 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of BAD in Rat Thymus cells with BAD antibody at 10 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemical staining of rat thymus using Bad at 2 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemical staining of rat thymus using Bad at 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of Bad in T24 cell lysates with Bad antibody at (A) 0.5, (B) 1, and (C) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of Bad in T24 cell lysates with Bad antibody at (A) 0.5, (B) 1, and (C) 2 μg/mL.)
Related Product Information for anti-BAD antibody
BAD Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain containing pro-apoptotic proteins, such as Bax, Bid, and Bik, form a growing subclass of the Bcl-2 family. Another such protein is the Bcl-2-antagonist of cell death (Bad). Bad regulates apoptosis by forming heterodimers with anti-apoptotic proteins Bcl-2 and Bcl-xL, thereby preventing them from binding with Bax. Bad activity is regulated by its phosphorylation; it is inactivated by kinases such as Akt and MAP kinase and thus promotes cell survival, whereas JNK-induced phosphorylation promotes the apoptotic role of Bad.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
18,392 Da
NCBI Official Full Name
Bcl2-associated agonist of cell death
NCBI Official Synonym Full Names
BCL2-associated agonist of cell death
NCBI Official Symbol
BAD
NCBI Official Synonym Symbols
BBC2; BCL2L8
NCBI Protein Information
bcl2-associated agonist of cell death; bcl2-L-8; BCL2-binding protein; bcl-2-like protein 8; BCL2-binding component 6; bcl-2-binding component 6; BCL-X/BCL-2 binding protein; bcl2 antagonist of cell death; BCL2-antagonist of cell death protein; bcl-XL/Bcl-2-associated death promoter
UniProt Protein Name
Bcl2-associated agonist of cell death
UniProt Gene Name
BAD
UniProt Synonym Gene Names
BBC6; BCL2L8; BAD; Bcl2-L-8
UniProt Entry Name
BAD_HUMAN
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Product Notes
The BAD bad (Catalog #AAA40308) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BAD Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's BAD can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the BAD bad for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BAD, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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