Application Data
BAD Polyclonal Antibody | anti-BAD antibody
BAD (Phospho-Ser136)
Gene Names
Bad; Bbc2; AI325008
Applications
Immunohistochemistry, Immunoblot, Western Blot
Synonyms
BAD, Antibody; BAD (Phospho-Ser136); anti-BAD antibody
Clonality
Polyclonal
Specificity
This antibody detects endogenous human, mouse, and rat BAD only when phosphorylated at serine 136.
Form/Format
100ul at 1.0mg/ml in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Affinity-purified on phosphopeptide; non-phosphopeptide- reactive antibodies were removed by chromatography on non-phosphorylated peptide.
Sequence Length
204
Applicable Applications for anti-BAD antibody
IHC (Immunohistochemistry), IB (Immunoblot)
Antigen
Peptide sequence that includes phosphorylation site of serine 136 (S-R-S(p)-A-P) derived from mouse BAD and conjugated to KLH.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Can be stored at 4 degree C for short-term.
Application Data
Application Data
IHC (Immunohistochemistry)
IHC (Immunohistochemistry)
Related Product Information for anti-BAD antibody
The protein encoded by the BAD gene is a member of the Bcl-2 family whose members are regulators of programmed cell death. BAD protein positively regulates cell apoptosis by forming heterodimers with Bcl-xL and Bcl-2 and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin, were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,080 Da
NCBI Official Full Name
bcl2-associated agonist of cell death isoform 1
NCBI Official Synonym Full Names
BCL2-associated agonist of cell death
NCBI Official Symbol
Bad
NCBI Official Synonym Symbols
Bbc2; AI325008
NCBI Protein Information
bcl2-associated agonist of cell death
UniProt Protein Name
Bcl2-associated agonist of cell death
UniProt Gene Name
Bad
UniProt Synonym Gene Names
Bbc6; BAD
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Product Notes
The BAD bad (Catalog #AAA47841) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's BAD can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IB (Immunoblot). Researchers should empirically determine the suitability of the BAD bad for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BAD, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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