IHC (Immunohiostchemistry)
(BAG2 Antibody (C-term) (AAA288809)immunohistochemistry analysis in formalin fixed and paraffin embedded human ovarian carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BAG2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit BAG2 Polyclonal Antibody | anti-BAG2 antibody
BAG2 Antibody (C-term)
Gene Names
BAG2; BAG-2; dJ417I1.2
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
BAG2, Antibody; BAG2 Antibody (C-term); BAG family molecular chaperone regulator 2; BAG-2; Bcl-2-associated athanogene 2; BAG2; anti-BAG2 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This BAG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 amino acids from the C-terminal region of human BAG2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
148-176
Sequence Length
211
Applicable Applications for anti-BAG2 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(BAG2 Antibody (C-term) (AAA288809)immunohistochemistry analysis in formalin fixed and paraffin embedded human ovarian carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BAG2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(BAG2 Antibody (C-term) (AAA288809)immunohistochemistry analysis in formalin fixed and paraffin embedded human ovarian carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BAG2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(BAG2 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the BAG2 antibody detected the BAG2 protein (arrow).)
WB (Western Blot)
(BAG2 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the BAG2 antibody detected the BAG2 protein (arrow).)
Related Product Information for anti-BAG2 antibody
BAG proteins compete with Hip for binding to the
Hsc70/Hsp70 ATPase domain and promote substrate release. All the
BAG proteins have an approximately 45-amino acid BAG domain near
the C terminus but differ markedly in their N-terminal regions. The
predicted BAG2 protein contains 211 amino acids. The BAG domains of
BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase
domain in vitro and in mammalian cells. All 3 proteins bind with
high affinity to the ATPase domain of Hsc70 and inhibit its
chaperone activity in a Hip-repressible manner. [provided by
RefSeq].
Hsc70/Hsp70 ATPase domain and promote substrate release. All the
BAG proteins have an approximately 45-amino acid BAG domain near
the C terminus but differ markedly in their N-terminal regions. The
predicted BAG2 protein contains 211 amino acids. The BAG domains of
BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase
domain in vitro and in mammalian cells. All 3 proteins bind with
high affinity to the ATPase domain of Hsc70 and inhibit its
chaperone activity in a Hip-repressible manner. [provided by
RefSeq].
Product Categories/Family for anti-BAG2 antibody
References
Arndt, V., et al. Mol. Biol. Cell 16(12):5891-5900(2005)
Dai, Q., et al. J. Biol. Chem. 280(46):38673-38681(2005)
Ueda, K., et al. J. Biol. Chem. 279(40):41815-41821(2004)
Ueda, K., et al. J. Biol. Chem. 279(40):41815-41821(2004)
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
Dai, Q., et al. J. Biol. Chem. 280(46):38673-38681(2005)
Ueda, K., et al. J. Biol. Chem. 279(40):41815-41821(2004)
Ueda, K., et al. J. Biol. Chem. 279(40):41815-41821(2004)
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23772
NCBI Official Full Name
BAG family molecular chaperone regulator 2
NCBI Official Synonym Full Names
BCL2-associated athanogene 2
NCBI Official Symbol
BAG2
NCBI Official Synonym Symbols
BAG-2; dJ417I1.2
NCBI Protein Information
BAG family molecular chaperone regulator 2
UniProt Protein Name
BAG family molecular chaperone regulator 2
UniProt Gene Name
BAG2
UniProt Synonym Gene Names
BAG-2
UniProt Entry Name
BAG2_HUMAN
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Product Notes
The BAG2 bag2 (Catalog #AAA288809) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 148-176. The BAG2 Antibody (C-term) reacts with Human (Predicted Reactivity: Bovine, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's BAG2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the BAG2 bag2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BAG2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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