WB (Western Blot)
(Fig: 2 Western blot analysis of BAG-3 in human pancreatic cencer cell lines using at 1: 2000.)
Rabbit BAG3 Polyclonal Antibody | anti-BAG3 antibody
Polyclonal Antibody to BAG3
Gene Names
BAG3; BIS; MFM6; BAG-3; CAIR-1
Reactivity
HumanPredicted: Mouse, Rat
Applications
Immunoprecipitation, Immunohistochemistry, Western Blot
Purity
Serum
Synonyms
BAG3, Antibody; Polyclonal Antibody to BAG3; BAG3; BIS; Bcl-2-associated athanogene 3; Bcl-2-binding protein Bis; Docking protein CAIR-1; Antibody to BAG3; Anti-BAG3 Antibody; BAG3 Antibody; anti-BAG3 antibody
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Predicted: Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Serum
Form/Format
50 ul sera
Sequence Length
575
Applicable Applications for anti-BAG3 antibody
IP (Immunoprecipitation), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Information
A synthetic peptide of human BAG-3 (amino acids 276-294 REGSPARSSTPLHSPSPIR) was used as immunogen for this antibody
Antigen
BAG3
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
WB (Western Blot)
(Fig: 2 Western blot analysis of BAG-3 in human pancreatic cencer cell lines using at 1: 2000.)
WB (Western Blot)
(Fig: 2 Western blot analysis of BAG-3 in human pancreatic cencer cell lines using at 1: 2000.)
WB (Western Blot)
(Fig: 1 Western blot analysis of BAG-3 in CAPAN-1 human pancreatic cancer cells following heat shock using at 1: 2000, Cells were heat shocked at 45 degrees for 10 min and total proteins were extracted following incubation at 37 degrees for the indicated times. Control = no heak shock treatment. Maximal BAG-3 protein expression was detected at 6 h post heat shock treatment.)
WB (Western Blot)
(Fig: 1 Western blot analysis of BAG-3 in CAPAN-1 human pancreatic cancer cells following heat shock using at 1: 2000, Cells were heat shocked at 45 degrees for 10 min and total proteins were extracted following incubation at 37 degrees for the indicated times. Control = no heak shock treatment. Maximal BAG-3 protein expression was detected at 6 h post heat shock treatment.)
Related Product Information for anti-BAG3 antibody
The BAG proteins are a family of chaperone regulators that modulate a number of diverse processes including proliferation, survival, stress responses, tumorigenesis, neuronal differentiation, growth arrest and apoptosis (reviewed Takayama and Reed, 2001; Doong et al, 2002, and Doukhanina et al. 2006). BAG proteins have been characterized as co-chaperones and interact with the chaperone heat shock proteins 70, both constitutive Hsc70 and inducible Hsp70. BAG proteins bind through their BAG domain to the ATPase domain of Hsc70/Hsp70, and can modulate either positively or negatively the functions of the Hsc70/Hsp70 chaperone proteins. The BAG domain has been shown to contribute to the anti-apoptotic activity of BAG- family proteins. The anti-apoptotic activities of BAG-family proteins may be dependent on their interactions with Hsc70/Asp70 and/or binding to Bcl-2. In addition to the conserved BAG domain, BAG-family proteins also contain additional domains which enable them to interact with specific target proteins or to target them to specific locations within cells.
Product Categories/Family for anti-BAG3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
61,595 Da
NCBI Official Full Name
BAG family molecular chaperone regulator 3
NCBI Official Synonym Full Names
BCL2 associated athanogene 3
NCBI Official Symbol
BAG3
NCBI Official Synonym Symbols
BIS; MFM6; BAG-3; CAIR-1
NCBI Protein Information
BAG family molecular chaperone regulator 3
UniProt Protein Name
BAG family molecular chaperone regulator 3
UniProt Gene Name
BAG3
UniProt Synonym Gene Names
BIS; BAG-3
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Product Notes
The BAG3 bag3 (Catalog #AAA78302) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to BAG3 reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's BAG3 can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the BAG3 bag3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BAG3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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