ICC (Immunocytochemistry)
(Immunocytochemistry staining of HL-60 cells using Bax at 2 ug/mL.)
Rabbit Bax Polyclonal Antibody | anti-Bax antibody
Bax Antibody
Gene Names
BAX; BCL2L4
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Immunocytochemistry, Western Blot, ELISA
Purity
Ion exchange chromatography purified
Synonyms
Bax, Antibody; Bax Antibody; anti-Bax antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Ion exchange chromatography purified
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
192
Applicable Applications for anti-Bax antibody
IHC (Immunohistochemistry), ICC (Immunocytochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a peptide corresponding to 16 amino acids near the amino-terminus of human Bax.
Target Name
Bax
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry staining of HL-60 cells using Bax at 2 ug/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry staining of HL-60 cells using Bax at 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of Bax in HL-60 cell lysates with Bax antibody at (A) 1, (B) 2, and (C) 4 ug/mL.)
WB (Western Blot)
(Western blot analysis of Bax in HL-60 cell lysates with Bax antibody at (A) 1, (B) 2, and (C) 4 ug/mL.)
Related Product Information for anti-Bax antibody
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bax, a pro-apoptotic Bcl-2 family member, is a cytosolic protein that changes conformation and translocates to the mitochondria following apoptotic stimuli. It is thought to share significant functional homology with Bak, another pro-apoptotic Bcl-2 family member, as disruption of bax or bak has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking both show decreased apoptotic capability.
Product Categories/Family for anti-Bax antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
19,718 Da
NCBI Official Full Name
Bax alpha
NCBI Official Synonym Full Names
BCL2-associated X protein
NCBI Official Symbol
BAX
NCBI Official Synonym Symbols
BCL2L4
NCBI Protein Information
apoptosis regulator BAX
UniProt Protein Name
Apoptosis regulator BAX
UniProt Gene Name
BAX
UniProt Synonym Gene Names
BCL2L4; Bcl2-L-4
UniProt Entry Name
BAX_HUMAN
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Product Notes
The Bax bax (Catalog #AAA304700) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Bax Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Bax can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the Bax bax for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bax, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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