IHC (Immunohiostchemistry)
(Fig: 2 Formalin-fixed, paraffin-embedded mouse tissue sections stained for Bax using at 1: 2000. A. Pancreas. B. Brain showing expression of Bax in the Purkinge cells.)
Rabbit anti-Rat, Mouse Bax Polyclonal Antibody | anti-BAX antibody
Polyclonal Antibody to Bax
Gene Names
BAX; BCL2L4
Reactivity
Rat, Mouse
Applications
Western Blot, Immunohistochemistry, Immunoprecipitation
Purity
Serum
Synonyms
Bax, Antibody; Polyclonal Antibody to Bax; BAX; BCL2L4; Bcl-2-like protein 4; Antibody to Bax; Anti-Bax Antibody; Bax Antibody; anti-BAX antibody
Host
Rabbit
Reactivity
Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Serum
Form/Format
50 ul sera
Sequence Length
192
Applicable Applications for anti-BAX antibody
WB (Western Blot), IHC (Immunohistochemistry), IP (Immunoprecipitation)
Immunogen Information
A synthetic peptide of Bax protein (amino acids 43-60 PELTLEQPPQDASTKKLS) was used as the immunogen for this antibody
Antigen
Bax
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
IHC (Immunohiostchemistry)
(Fig: 2 Formalin-fixed, paraffin-embedded mouse tissue sections stained for Bax using at 1: 2000. A. Pancreas. B. Brain showing expression of Bax in the Purkinge cells.)
IHC (Immunohiostchemistry)
(Fig: 2 Formalin-fixed, paraffin-embedded mouse tissue sections stained for Bax using at 1: 2000. A. Pancreas. B. Brain showing expression of Bax in the Purkinge cells.)
WB (Western Blot)
(Fig: 1 Western blot analysis of Bax in mouse using at 1: 2000. 1. In vitro translated mouse Bax. 2. Normal cortex. 3. Ischemic hippocampus. 4. Ischemic hippocampus. Ishemic samples were prepared 6 hr post middle cerebral artery occlusion. The results show the Bax expression increased following ischemia.)
WB (Western Blot)
(Fig: 1 Western blot analysis of Bax in mouse using at 1: 2000. 1. In vitro translated mouse Bax. 2. Normal cortex. 3. Ischemic hippocampus. 4. Ischemic hippocampus. Ishemic samples were prepared 6 hr post middle cerebral artery occlusion. The results show the Bax expression increased following ischemia.)
Related Product Information for anti-BAX antibody
This antibody reacts with Bax isoforms containing the peptide immunogen sequence (PELTLEQPPQDASTKKLS). Mouse and rat Bax alpha are 192 amino acid proteins. The Bcl-2 family of apoptosis-related genes plays central roles in regulating apoptotic pathways. Regulation of cell death through apoptosis is critical for the maintenance of homeostasis, defense against infectious agents, and normal development. Bcl-2 family proteins regulate apoptosis primarily through the regulation of mitochondrial outer membrane permeability. In mammals, Bcl-2 family proteins can be divided into 3 main subfamilies on the basis of their function and the content of their Bcl-2 homology (BH) domains, for example: 1) Prosurvival: Bcl-2, Bcl-XL, Bcl-W, A1, and Mcl-1 2) Proapoptotic (multidomain): Bax, Bak, and Bok. 3) BH3-only (proapoptotic): Bad, Bcl-XS, Bid, Bik, Bim, Blk, Bmf, Bnip, Noxa, and Puma. Many Bcl-2 family proteins are differentially expressed in various malignancies and some are useful prognostic biomarkers. Prosurvival proteins are often elevated in diverse cancers and have the potential to confer resistance to both endogenous cell death stimuli and cancer treatments. Alterations in the ratio or levels of Bcl-2 family proteins have been also associated with nonmalignant diseases including neurodegenerative diseases, autoimmune diseases, AIDs, Downs syndrome, cardiovascular diseases, diabetes, glomerulonephritis, and muscular dystrophy.
Product Categories/Family for anti-BAX antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
19,718 Da
NCBI Official Full Name
Apoptosis regulator BAX
NCBI Official Synonym Full Names
BCL2 associated X, apoptosis regulator
NCBI Official Symbol
BAX
NCBI Official Synonym Symbols
BCL2L4
NCBI Protein Information
apoptosis regulator BAX
UniProt Protein Name
Apoptosis regulator BAX
UniProt Gene Name
BAX
UniProt Synonym Gene Names
BCL2L4; Bcl2-L-4
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Product Notes
The BAX bax (Catalog #AAA78308) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Bax reacts with Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Bax can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), IP (Immunoprecipitation). Researchers should empirically determine the suitability of the BAX bax for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bax, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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