ICC (Immunocytochemistry)
(Immunocytochemistry of Bcl-2 in A20 cells with Bcl-2 antibody at 2 μg/mL.)
Rabbit anti-Human Bcl-2 Polyclonal Antibody | anti-BCL2 antibody
Bcl-2 Antibody
Gene Names
BCL2; Bcl-2; PPP1R50
Reactivity
Human
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
Bcl-2 Antibody is affinity chromatography purified via peptide column.
Synonyms
Bcl-2, Antibody; Bcl-2 Antibody; Bcl-2; PPP1R50; Apoptosis regulator Bcl-2; B-cell CLL/lymphoma 2; anti-BCL2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Bcl-2 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
239
Applicable Applications for anti-BCL2 antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
Bcl-2 antibody was raised against a peptide corresponding to 14 amino acids near the middle of human Bcl-2.
Buffer
Bcl-2 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
Bcl-2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of Bcl-2 in A20 cells with Bcl-2 antibody at 2 μg/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of Bcl-2 in A20 cells with Bcl-2 antibody at 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of Bcl-2 in (A) Daudi and (B) A-20 cell lysates with Bcl-2 antibody at 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of Bcl-2 in (A) Daudi and (B) A-20 cell lysates with Bcl-2 antibody at 2 μg/mL.)
Related Product Information for anti-BCL2 antibody
Bcl-2 Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Bcl-2 is the founding member of a family of over 20 proteins that are critical regulators of apoptosis. These can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bcl-2 is an inner mitochondrial membrane protein that inhibits apoptosis. It is thought to act by interacting with pro-apoptotic Bcl-2 family members such as Bak and Bad. Overexpression of Bcl-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
22,337 Da
NCBI Official Full Name
B-cell CLL/lymphoma 2
NCBI Official Synonym Full Names
B-cell CLL/lymphoma 2
NCBI Official Symbol
BCL2
NCBI Official Synonym Symbols
Bcl-2; PPP1R50
NCBI Protein Information
apoptosis regulator Bcl-2; protein phosphatase 1, regulatory subunit 50
UniProt Protein Name
Apoptosis regulator Bcl-2
UniProt Gene Name
BCL2
UniProt Entry Name
BCL2_HUMAN
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Product Notes
The BCL2 bcl2 (Catalog #AAA39955) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Bcl-2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Bcl-2 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the BCL2 bcl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bcl-2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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