WB (Western Blot)
(Western blot analysis of BCL11A in lysates of Jurkat, using BCL11A Antibody.)
Rabbit BCL11A Polyclonal Antibody | anti-BCL11A antibody
BCL11A Antibody
Gene Names
BCL11A; EVI9; CTIP1; DILOS; ZNF856; HBFQTL5; BCL11A-L; BCL11A-S; BCL11a-M; BCL11A-XL
Reactivity
Human, Mouse, RatPredicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Applications
ELISA, Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
BCL11A, Antibody; BCL11A Antibody; 2810047E18Rik; B cell CLL/lymphoma 11A (zinc finger protein); B cell CLL/lymphoma 11A (zinc finger protein) isoform 2; B-cell CLL/lymphoma 11A; B-cell lymphoma/leukemia 11A; BC11A_HUMAN; BCL-11A; BCL11A; BCL11A B cell CLL/lymphoma 11A (zinc finger protein) isoform 1; BCL11A L; BCL11A S; BCL11A XL; BCL11a-M; BCL11AL; BCL11AS; BCL11AXL; C2H2 type zinc finger protein; COUP TF interacting protein 1; COUP-TF-interacting protein 1; CTIP1; CTIP1, mouse, homolog of; D930021L15Rik; Ecotropic viral integration site 9; Ecotropic viral integration site 9 homolog; Ecotropic viral integration site 9 protein; Ecotropic viral integration site 9 protein homolog; EVI-9; Evi9; Evi9, mouse, homolog of; FLJ10173; FLJ34997; HBFQTL5; KIAA1809; mKIAA1809; OTTHUMP00000159788; OTTHUMP00000159789; OTTHUMP00000201250; OTTHUMP00000202084; Zinc finger protein 856; ZNF856; anti-BCL11A antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Clonality
Polyclonal
Isotype
IgG
Specificity
BCL11A Antibody detects endogenous levels of BCL11A.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
773
Applicable Applications for anti-BCL11A antibody
ELISA (Peptide ELISA), WB (Western Blot)
Immunogen
A synthesized peptide derived from human BCL11A.
Tissue Specificity
Expressed at high levels in brain, spleen thymus, bone marrow and testis. Expressed in CD34-positive myeloid precursor cells, B-cells, monocytes and megakaryocytes. Expression is tightly regulated during B-cell development.
Subcellular Location
Nucleus; Nucleus; Nucleus
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
WB (Western Blot)
(Western blot analysis of BCL11A in lysates of Jurkat, using BCL11A Antibody.)
WB (Western Blot)
(Western blot analysis of BCL11A in lysates of Jurkat, using BCL11A Antibody.)
WB (Western Blot)
(Western blot analysis of extracts from various samples, using BCL11A Antibody.Lane 1: EC304, treated with blocking peptide;Lane 2: EC304;Lane 3: Mouse testis.)
WB (Western Blot)
(Western blot analysis of extracts from various samples, using BCL11A Antibody.Lane 1: EC304, treated with blocking peptide;Lane 2: EC304;Lane 3: Mouse testis.)
Related Product Information for anti-BCL11A antibody
Description: Transcription factor associated with the BAF SWI/SNF chromatin remodeling complex (By similarity). Repressor of fetal hemoglobin (HbF) level (PubMed:26375765). Involved in brain development (PubMed:27453576). Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. Essential factor in lymphopoiesis required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1 (By similarity).
Post Translational Modifications: Sumoylated with SUMO1.
Subunit Structure: Interacts with TFCOUP1, PIAS3, ARP1 and EAR2 (By similarity). Isoform 1, isoform 2 and isoform 3 form homodimers and heterodimers (PubMed:27453576).
Similarity: The N-terminus is involved in protein dimerization and in transactivation of transcription.
Post Translational Modifications: Sumoylated with SUMO1.
Subunit Structure: Interacts with TFCOUP1, PIAS3, ARP1 and EAR2 (By similarity). Isoform 1, isoform 2 and isoform 3 form homodimers and heterodimers (PubMed:27453576).
Similarity: The N-terminus is involved in protein dimerization and in transactivation of transcription.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 91 kDa
Predicted: 92 kDa
Predicted: 92 kDa
NCBI Official Full Name
B-cell lymphoma/leukemia 11A isoform 2
NCBI Official Synonym Full Names
BAF chromatin remodeling complex subunit BCL11A
NCBI Official Symbol
BCL11A
NCBI Official Synonym Symbols
EVI9; CTIP1; DILOS; ZNF856; HBFQTL5; BCL11A-L; BCL11A-S; BCL11a-M; BCL11A-XL
NCBI Protein Information
B-cell lymphoma/leukemia 11A
UniProt Protein Name
B-cell lymphoma/leukemia 11A
UniProt Gene Name
BCL11A
UniProt Synonym Gene Names
CTIP1; EVI9; KIAA1809; ZNF856; BCL-11A; EVI-9
UniProt Entry Name
BC11A_HUMAN
Similar Products
Product Notes
The BCL11A bcl11a (Catalog #AAA328564) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BCL11A Antibody reacts with Human, Mouse, Rat Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus and may cross-react with other species as described in the data sheet. AAA Biotech's BCL11A can be used in a range of immunoassay formats including, but not limited to, ELISA (Peptide ELISA), WB (Western Blot). Researchers should empirically determine the suitability of the BCL11A bcl11a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCL11A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.