IP (Immunoprecipitation)
(Detection of human Beta-Arrestin 2 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HEK293T cells. Antibodies: Affinity purified rabbit anti-Beta-Arrestin 2 antibody AAA212285 used for IP at 6 ug/mg lysate. Beta-Arrestin 2 was also immunoprecipitated by rabbit anti-Beta-Arrestin 2 antibody which recognizes a downstream epitope. For blotting Beta-Arrestin 2, was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 seconds.)
Rabbit anti-Human Beta-Arrestin 2 Polyclonal Antibody | anti-ARRB2 antibody
Rabbit anti-Beta-Arrestin 2 Antibody, Affinity Purified
Gene Names
ARRB2; ARB2; ARR2; BARR2
Reactivity
Human
Applications
Immunohistochemistry, Immunoprecipitation
Purity
Antigen Affinity Purified
Synonyms
Beta-Arrestin 2, Antibody; Rabbit anti-Beta-Arrestin 2 Antibody, Affinity Purified; ARB2; non-visual arrestin-3; beta-arrestin-2; BARR2; Arrestin beta-2; ARR2; arrestin 3; Beta-arrestin-2; arrestin beta 2; anti-ARRB2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Concentration
1000ug/ml (varies by lot)
Applicable Applications for anti-ARRB2 antibody
IHC (Immunohistochemistry), IP (Immunoprecipitation)
Predicted Reactivity
Orangutan
Immunogen
Between 359 and C-terminus
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Shelf Life: 1 year from date of receipt
IP (Immunoprecipitation)
(Detection of human Beta-Arrestin 2 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HEK293T cells. Antibodies: Affinity purified rabbit anti-Beta-Arrestin 2 antibody AAA212285 used for IP at 6 ug/mg lysate. Beta-Arrestin 2 was also immunoprecipitated by rabbit anti-Beta-Arrestin 2 antibody which recognizes a downstream epitope. For blotting Beta-Arrestin 2, was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 seconds.)
IP (Immunoprecipitation)
(Detection of human Beta-Arrestin 2 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HEK293T cells. Antibodies: Affinity purified rabbit anti-Beta-Arrestin 2 antibody AAA212285 used for IP at 6 ug/mg lysate. Beta-Arrestin 2 was also immunoprecipitated by rabbit anti-Beta-Arrestin 2 antibody which recognizes a downstream epitope. For blotting Beta-Arrestin 2, was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 seconds.)
IHC (Immunohiostchemistry)
(Detection of human Beta-Arrestin 2 by immunohistochemistry. Samples: FFPE sections of human breast carcinoma. Antibody: Affinity purified rabbit anti-Beta-Arrestin 2 Cat. No. AAA212285 Lot1 used at a dilution of 1:1,000 (1ug/ml) (left) and Cat. No. Lot1 used at a dilution of 1:1,000 (1ug/ml) (right). Detection: DAB)
IHC (Immunohiostchemistry)
(Detection of human Beta-Arrestin 2 by immunohistochemistry. Samples: FFPE sections of human breast carcinoma. Antibody: Affinity purified rabbit anti-Beta-Arrestin 2 Cat. No. AAA212285 Lot1 used at a dilution of 1:1,000 (1ug/ml) (left) and Cat. No. Lot1 used at a dilution of 1:1,000 (1ug/ml) (right). Detection: DAB)
IHC (Immunohistochemistry)
(Detection of human Beta-Arrestin 2 by immunohistochemistry. Samples: FFPE sections of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-Beta-Arrestin 2 Cat. No. AAA212285 Lot1 used at a dilution of 1:1,000 (1ug/ml) (left) and Cat. No. Lot1 used at a dilution of 1:1,000 (1ug/ml) (right). Detection: DAB)
IHC (Immunohistochemistry)
(Detection of human Beta-Arrestin 2 by immunohistochemistry. Samples: FFPE sections of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-Beta-Arrestin 2 Cat. No. AAA212285 Lot1 used at a dilution of 1:1,000 (1ug/ml) (left) and Cat. No. Lot1 used at a dilution of 1:1,000 (1ug/ml) (right). Detection: DAB)
Related Product Information for anti-ARRB2 antibody
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Beta-arrestin 2, like beta-arrestin 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for beta-arrestin 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. [taken from NCBI Entrez Gene (Gene ID: 409)].
Product Categories/Family for anti-ARRB2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,106 Da
NCBI Official Full Name
beta-arrestin-2 isoform 2
NCBI Official Synonym Full Names
arrestin, beta 2
NCBI Official Symbol
ARRB2
NCBI Official Synonym Symbols
ARB2; ARR2; BARR2
NCBI Protein Information
beta-arrestin-2; arrestin 3; arrestin beta-2
UniProt Protein Name
Beta-arrestin-2
UniProt Gene Name
ARRB2
UniProt Synonym Gene Names
ARB2; ARR2
UniProt Entry Name
ARRB2_HUMAN
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Product Notes
The ARRB2 arrb2 (Catalog #AAA212285) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-Beta-Arrestin 2 Antibody, Affinity Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Beta-Arrestin 2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IP (Immunoprecipitation). Researchers should empirically determine the suitability of the ARRB2 arrb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Beta-Arrestin 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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