WB (Western Blot)
(Western blot analysis of different tissue lysates using rabbit pAb to beta-synuclein, RA22141, dilution 1:1,000 in green: [1] protein standard (red), [2] mouse cerebellum [3] mouse hippocampus, [4] rat cerebellum, [5] rat hippocampus, and [6] cow cerebellum. Strong band at about 17kDa corresponds to the beta-synuclein protein.)
Rabbit Beta-Synuclein Polyclonal Antibody | anti-SNCB antibody
Beta-Synuclein
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Western Blot, Immunocytochemistry
Synonyms
Beta-Synuclein, Antibody; Beta-Synuclein; anti-SNCB antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Form/Format
Affinity Purified antibody
Liquid. Purified antibody at 1mg/mL in 50% PBS, 50% glycerol plus 5mM NaN3
Liquid. Purified antibody at 1mg/mL in 50% PBS, 50% glycerol plus 5mM NaN3
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-SNCB antibody
IF (Immunofluorescence), WB (Western Blot), ICC (Immunocytochemistry)
Immunogen
C-terminal peptide of human beta-synuclein EPEGESYEDPPQEEYQEYEPEA coupled to KLH
Preparation and Storage
Antibody can also be aliquotted and stored frozen at -20 degree C in a manual defrost freezer for six months without detectable loss of activity. The antibody is stableat 2-8 degree C for 1 year. Avoid repeated freeze-thaw cycles.
WB (Western Blot)
(Western blot analysis of different tissue lysates using rabbit pAb to beta-synuclein, RA22141, dilution 1:1,000 in green: [1] protein standard (red), [2] mouse cerebellum [3] mouse hippocampus, [4] rat cerebellum, [5] rat hippocampus, and [6] cow cerebellum. Strong band at about 17kDa corresponds to the beta-synuclein protein.)
WB (Western Blot)
(Western blot analysis of different tissue lysates using rabbit pAb to beta-synuclein, RA22141, dilution 1:1,000 in green: [1] protein standard (red), [2] mouse cerebellum [3] mouse hippocampus, [4] rat cerebellum, [5] rat hippocampus, and [6] cow cerebellum. Strong band at about 17kDa corresponds to the beta-synuclein protein.)
IF (Immunofluorescence)
(Immunofluorescent analysis of rat cerebellum section stained with rabbit pAb to beta-synuclein dilution 1:1,000 in red, and costained with chicken pAb to parvalbumin dilution 1:5,000 in green. The blue is Hoechst staining of nuclear DNA. The beta-synuclein antibody detects protein concentrated in synaptic regions, and parvalbumin antibody labels the perikarya and dendrites of Purkinje cells, and interneurons in the molecular layer of the cerebellum.)
IF (Immunofluorescence)
(Immunofluorescent analysis of rat cerebellum section stained with rabbit pAb to beta-synuclein dilution 1:1,000 in red, and costained with chicken pAb to parvalbumin dilution 1:5,000 in green. The blue is Hoechst staining of nuclear DNA. The beta-synuclein antibody detects protein concentrated in synaptic regions, and parvalbumin antibody labels the perikarya and dendrites of Purkinje cells, and interneurons in the molecular layer of the cerebellum.)
Related Product Information for anti-SNCB antibody
beta-synuclein is a member of the synuclein protein family, the other two members being alpha and gamma-synuclein, each protein being coded for by a distinct but related gene. alpha-synuclein was originally isolated as a major synaptic vesicle associated protein from the electric organ of the fish Torpedo, and direct homologues of alpha-synuclein are found in all vertebrates. Later work connected alpha-synuclein expression with several human brain pathologies, so that it is a major component of the Lewy bodies of Parkinson's disease. beta-synuclein was isolated as a component of normal and diseased human brain as a protein clearly related to but distinct from alpha-synuclein. The human beta-synuclein molecule is 134 amino acids in size compared to 140 amino acids for alpha-synuclein, and the N-terminal halves of the two molecules are virtually identical while the C-terminal regions is more variable.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
14,288 Da
NCBI Official Full Name
beta-synuclein
NCBI Official Synonym Full Names
synuclein, beta
NCBI Official Symbol
SNCB
NCBI Protein Information
beta-synuclein
UniProt Protein Name
Beta-synuclein
UniProt Gene Name
SNCB
UniProt Entry Name
SYUB_HUMAN
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Product Notes
The SNCB sncb (Catalog #AAA76695) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Beta-Synuclein reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Beta-Synuclein can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ICC (Immunocytochemistry). Researchers should empirically determine the suitability of the SNCB sncb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Beta-Synuclein, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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