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IHC (Immunohistochemistry)
(BIRC3 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BIRC3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human BIRC3 Polyclonal Antibody | anti-BIRC3 antibody
BIRC3 Antibody (N-term)
Gene Names
BIRC3; AIP1; API2; MIHC; CIAP2; HAIP1; HIAP1; MALT2; RNF49; c-IAP2
Reactivity
Human
Applications
Immunohistochemistry, Immunofluorescence, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
BIRC3, Antibody; BIRC3 Antibody (N-term); Baculoviral IAP repeat-containing protein 3; 632-; Apoptosis inhibitor 2; API2; C-IAP2; IAP homolog C; Inhibitor of apoptosis protein 1; IAP-1; hIAP-1; hIAP1; RING finger protein 49; TNFR2-TRAF-signaling complex protein 1; BIRC3; IAP1; MIHC; RNF49; anti-BIRC3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This BIRC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-88 amino acids from the N-terminal region of human BIRC3.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
59-88
Sequence Length
604
Applicable Applications for anti-BIRC3 antibody
IHC (Immunohistochemistry), IF (Immunofluorescence), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohistochemistry)
(BIRC3 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BIRC3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohistochemistry)
(BIRC3 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BIRC3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IF (Immunofluorescence)
(Confocal immunofluorescent analysis of BIRC3 Antibody (N-term) with MDA-MB435 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).)
IF (Immunofluorescence)
(Confocal immunofluorescent analysis of BIRC3 Antibody (N-term) with MDA-MB435 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).)
WB (Western Blot)
(Western blot analysis of BIRC3 (arrow) using rabbit polyclonal BIRC3 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the BIRC3 gene.)
WB (Western Blot)
(Western blot analysis of BIRC3 (arrow) using rabbit polyclonal BIRC3 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the BIRC3 gene.)
WB (Western Blot)
(BIRC3 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the BIRC3 antibody detected the BIRC3 protein (arrow).)
WB (Western Blot)
(BIRC3 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the BIRC3 antibody detected the BIRC3 protein (arrow).)
Related Product Information for anti-BIRC3 antibody
The protein encoded by this gene is a member of a family
of proteins that inhibits apoptosis by binding to tumor necrosis
factor receptor-associated factors TRAF1 and TRAF2, probably by
interfering with activation of ICE-like proteases. The encoded
protein inhibits apoptosis induced by serum deprivation but does
not affect apoptosis resulting from exposure to menadione, a potent
inducer of free radicals. The amino acid sequence predicts three
baculovirus IAP repeat domains and a ring finger domain. Transcript
variants encoding the same isoform have been identified. [provided
by RefSeq].
of proteins that inhibits apoptosis by binding to tumor necrosis
factor receptor-associated factors TRAF1 and TRAF2, probably by
interfering with activation of ICE-like proteases. The encoded
protein inhibits apoptosis induced by serum deprivation but does
not affect apoptosis resulting from exposure to menadione, a potent
inducer of free radicals. The amino acid sequence predicts three
baculovirus IAP repeat domains and a ring finger domain. Transcript
variants encoding the same isoform have been identified. [provided
by RefSeq].
Product Categories/Family for anti-BIRC3 antibody
References
Zane, L., et al. Virology 407(2):341-351(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Kim, C.W., et al. Biochem. Biophys. Res. Commun. 400(1):46-52(2010)
Petersen, S.L., et al. Proc. Natl. Acad. Sci. U.S.A. 107(26):11936-11941(2010)
Friboulet, L., et al. BMC Cancer 10, 327 (2010) :
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Kim, C.W., et al. Biochem. Biophys. Res. Commun. 400(1):46-52(2010)
Petersen, S.L., et al. Proc. Natl. Acad. Sci. U.S.A. 107(26):11936-11941(2010)
Friboulet, L., et al. BMC Cancer 10, 327 (2010) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
68372
NCBI Official Full Name
baculoviral IAP repeat-containing protein 3
NCBI Official Synonym Full Names
baculoviral IAP repeat containing 3
NCBI Official Symbol
BIRC3
NCBI Official Synonym Symbols
AIP1; API2; MIHC; CIAP2; HAIP1; HIAP1; MALT2; RNF49; c-IAP2
NCBI Protein Information
baculoviral IAP repeat-containing protein 3
UniProt Protein Name
Baculoviral IAP repeat-containing protein 3
UniProt Gene Name
BIRC3
UniProt Synonym Gene Names
API2; IAP1; MIHC; RNF49; API2; IAP-1; hIAP-1; hIAP1
UniProt Entry Name
BIRC3_HUMAN
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Product Notes
The BIRC3 birc3 (Catalog #AAA283612) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 59-88. The BIRC3 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BIRC3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IF (Immunofluorescence), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the BIRC3 birc3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BIRC3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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