Rabbit anti-Human, Mouse BTK Polyclonal Antibody | anti-BTK antibody

BTK Antibody

Cat. Num. AAA39632

• Gene Names: BTK; AT; ATK; BPK; XLA; IMD1; AGMX1; PSCTK1
• Reactivity: Human, Mouse
• Applications: Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
• Purity: BTK Antibody is affinity chromatography purified via peptide column.
• Synonyms: BTK, Antibody; BTK Antibody; BTK; AT; ATK; BPK; XLA; IMD1; AGMX1; PSCTK1; Tyrosine-protein kinase BTK; Agammaglobulinemia tyrosine kinase; Bruton agammaglobulinemia tyrosine kinase; anti-BTK antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Multiple isoforms of BTK are known to exist.
• Purity/Purification: BTK Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 659

• Applicable Applications for anti-BTK antibody: IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: BTK antibody was raised against a synthetic peptide corresponding to 16 amino acids near the amino-terminus of human BTK.
• Buffer: BTK Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: BTK antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of BTK in mouse brain tissue with BTK antibody at 20 μg/ml.Red: BTK Antibody (3395)Blue: DAPI staining)

ICC (Immunocytochemistry)

(Immunocytochemistry of BTK in Daudi cells with BTK antibody at 10 μg/mL.)

IF (Immunofluorescence)

(Immunofluorescence of BTK in Daudi cells with BTK antibody at 10 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of BTK in mouse brain tissue with BTK antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of BTK in U937 cell lysate with BTK antibody at (A) 0.5, (B) 1, and (C) 2 μg/mL.)

Related Product Information for anti-BTK antibody

BTK Antibody: Bruton's tyrosine kinase (BTK) was initially identified as a member of the src family for protein-tyrosine kinases that was involved in X-linked agamma-globulinaemia, and has since been shown to involved in a number of signaling pathways in hemapoietic lineage. It has recently been shown to interact with members of the toll-like receptor (TLR) family such as TLR4, 6, 8, and 9. The TLRs are critical molecules in both the innate and adaptive immunity and can recognize diverse microbial pathogens. BTK has also been shown to interact with key proteins involved in TLR4 signal transduction such as MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting that BTK is involved in lipopolysaccharide signal transduction.

NCBI and Uniprot Product Information

• NCBI GI #: 547759
• NCBI GeneID: 695
• UniProt Accession #: Q06187; Q32ML5; B2RAW1
• Molecular Weight: Predicted: 76 kDa; ; Observed: 79 kDa
• NCBI Official Full Name: Tyrosine-protein kinase BTK
• NCBI Official Synonym Full Names: Bruton agammaglobulinemia tyrosine kinase
• NCBI Official Symbol: BTK
• NCBI Official Synonym Symbols: AT; ATK; BPK; XLA; IMD1; AGMX1; PSCTK1
• NCBI Protein Information: tyrosine-protein kinase BTK; B-cell progenitor kinase; agammaglobulinaemia tyrosine kinase; truncated Bruton agammaglobulinemia tyrosine kinase; tyrosine-protein kinase BTK isoform (lacking exon 14); dominant-negative kinase-deficient Brutons tyrosine kinase
• UniProt Protein Name: Tyrosine-protein kinase BTK
• UniProt Gene Name: BTK
• UniProt Synonym Gene Names: AGMX1; ATK; BPK; ATK; BPK
• UniProt Entry Name: BTK_HUMAN