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IHC (Immunohistochemistry)
(Anti- KCNMA1antibody, AAA46094,IHC(P)IHC(P): Human Lung Cancer Tissue)
Rabbit Calcium-activated potassium channel subunit alpha-1 Polyclonal Antibody | anti-KCNMA1 antibody
Anti-KCNMA1 Antibody
Gene Names
KCNMA1; SLO; BKTM; SLO1; MaxiK; SAKCA; mSLO1; KCa1.1; SLO-ALPHA; bA205K10.1
Reactivity
Human, Mouse, Rat. No cross reactivity with other proteins.
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Calcium-activated potassium channel subunit alpha-1, Antibody; Anti-KCNMA1 Antibody; subfamily M subunit alpha-1 antibody; bA205K10.1 antibody; BK channel antibody; BKCA alpha antibody; BKCA alpha subunit antibody; BKTM antibody; Calcium activated potassium channel subfamily M subunit alpha 1 antibody; Calcium activated potassium channel subunit alpha 1 antibody; Calcium-activated potassium channel antibody; Calcium-activated potassium channel subunit alpha-1 antibody; DKFZp686K1437 antibody; Drosophila slowpoke like antibody; hSlo antibody; K(VCA)alpha antibody; KCa1.1 antibody; KCMA1_HUMAN antibody; KCNMA 1 antibody; KCNMA antibody; KCNMA1 antibody; Large conductance calcium activated potassium channel subfamily M alpha member 1 antibody; Maxi K antibody; Maxi K channel antibody; Maxi Potassium channel alpha antibody; MaxiK antibody; MGC71881 antibody; OTTHUMP00000060198 antibody; OTTHUMP00000064154 antibody; OTTHUMP00000064155 antibody; OTTHUMP00000064156 antibody; OTTHUMP00000064157 antibody; OTTHUMP00000064158 antibody; OTTHUMP00000064159 antibody; OTTHUMP00000064160 antibody; OTTHUMP00000064161 antibody; OTTHUMP00000064162 antibody; OTTHUMP00000064164 antibody; OTTHUMP00000064165 antibody; Potassium large conductance calcium activated channel subfamily M alpha member 1 antibody; SAKCA antibody; Slo 1 antibody; SLO alpha antibody; SLO antibody; Slo homolog antibody; Slo-alpha antibody; Slo1 antibody; Slowpoke homolog antibody; Stretch activated Kca channel antibody; potassium large conductance calcium-activated channel, subfamily M, alpha member 1; anti-KCNMA1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat. No cross reactivity with other proteins.
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
1182
Applicable Applications for anti-KCNMA1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Immunogen
E.coli-derived human KCNMA1 recombinant protein (Position: K124-Q467). Human KCNMA1 shares 99% amino acid (aa) sequence identity with both mouse and rat KCNMA1.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohistochemistry)
(Anti- KCNMA1antibody, AAA46094,IHC(P)IHC(P): Human Lung Cancer Tissue)
IHC (Immunohistochemistry)
(Anti- KCNMA1antibody, AAA46094,IHC(P)IHC(P): Human Lung Cancer Tissue)
IHC (Immunohistochemisry)
(Anti- KCNMA1antibody, AAA46094,IHC(P)IHC(P): Rat Intestine Tissue)
IHC (Immunohistochemisry)
(Anti- KCNMA1antibody, AAA46094,IHC(P)IHC(P): Rat Intestine Tissue)
IHC (Immunohiostchemistry)
(Anti- KCNMA1antibody, AAA46094,IHC(P)IHC(P): Mouse Intestine Tissue)
IHC (Immunohiostchemistry)
(Anti- KCNMA1antibody, AAA46094,IHC(P)IHC(P): Mouse Intestine Tissue)
WB (Western Blot)
(Anti- KCNMA1antibody, AAA46094, Western blottingAll lanes: Anti KCNMA1 (AAA46094) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 50ugLane 2: Rat Testis Tissue Lysate at 50ugLane 3: Mouse Brain Tissue Lysate at 50ugLane 4: Mouse Testis Tissue Lysate at 50ugPredicted bind size: 137KDObserved bind size: 70KD)
WB (Western Blot)
(Anti- KCNMA1antibody, AAA46094, Western blottingAll lanes: Anti KCNMA1 (AAA46094) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 50ugLane 2: Rat Testis Tissue Lysate at 50ugLane 3: Mouse Brain Tissue Lysate at 50ugLane 4: Mouse Testis Tissue Lysate at 50ugPredicted bind size: 137KDObserved bind size: 70KD)
Related Product Information for anti-KCNMA1 antibody
Description: Rabbit IgG polyclonal antibody for Calcium-activated potassium channel subunit alpha-1(KCNMA1) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
Background: Calcium-activated potassium channel subunit alpha-1 also known as KCa1.1, or BK channel for short, is a voltage gated potassium channel encoded by the KCNMA1 gene and characterized by their large conductance of potassium ions (K+) through cell membranes. This gene is located on 10q22.3. BK channels are activated (opened) by changes in membrane electrical potential and/or by increases in concentration of intracellular calcium ion (Ca2+). It is essential for the regulation of several key physiological processes including smooth muscle tone and neuronal excitability. BK channels also contribute to the behavioral effects of ethanol in the worm C. elegans under high concentrations (> 100 mM, or approximately 0.50% BAC).It remains to be determined if BK channels contribute to intoxication in humans.
Background: Calcium-activated potassium channel subunit alpha-1 also known as KCa1.1, or BK channel for short, is a voltage gated potassium channel encoded by the KCNMA1 gene and characterized by their large conductance of potassium ions (K+) through cell membranes. This gene is located on 10q22.3. BK channels are activated (opened) by changes in membrane electrical potential and/or by increases in concentration of intracellular calcium ion (Ca2+). It is essential for the regulation of several key physiological processes including smooth muscle tone and neuronal excitability. BK channels also contribute to the behavioral effects of ethanol in the worm C. elegans under high concentrations (> 100 mM, or approximately 0.50% BAC).It remains to be determined if BK channels contribute to intoxication in humans.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
138,297 Da
NCBI Official Full Name
calcium-activated potassium channel subunit alpha-1 isoform a
NCBI Official Synonym Full Names
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
NCBI Official Symbol
KCNMA1
NCBI Official Synonym Symbols
SLO; BKTM; SLO1; MaxiK; SAKCA; mSLO1; KCa1.1; SLO-ALPHA; bA205K10.1
NCBI Protein Information
calcium-activated potassium channel subunit alpha-1; uncharacterized protein; hSlo; k(VCA)alpha; slo homolog; slowpoke homolog; BKCA alpha subunit; maxi-K channel HSLO; BK channel alpha subunit; stretch-activated Kca channel; calcium-activated potassium channel, subfamily M subunit alpha-1
UniProt Protein Name
Calcium-activated potassium channel subunit alpha-1
UniProt Gene Name
KCNMA1
UniProt Synonym Gene Names
KCNMA; SLO; MaxiK; Slo homolog; hSlo
UniProt Entry Name
KCMA1_HUMAN
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Product Notes
The KCNMA1 kcnma1 (Catalog #AAA46094) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-KCNMA1 Antibody reacts with Human, Mouse, Rat. No cross reactivity with other proteins. and may cross-react with other species as described in the data sheet. AAA Biotech's Calcium-activated potassium channel subunit alpha-1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the KCNMA1 kcnma1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Calcium-activated potassium channel subunit alpha-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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