IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with CAMKK2 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Rabbit anti-Human CAMKK2 Polyclonal Antibody | anti-CAMKK2 antibody
CAMKK2 Antibody (N-term G67)
Gene Names
CAMKK2; CAMKK; CAMKKB
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CAMKK2, Antibody; CAMKK2 Antibody (N-term G67); Calcium/calmodulin-dependent protein kinase kinase 2; CaM-KK 2; CaM-kinase kinase 2; CaMKK 2; Calcium/calmodulin-dependent protein kinase kinase beta; CaM-KK beta; CaM-kinase kinase beta; CaMKK beta; CAMKK2; CAMKKB; KIAA0787; anti-CAMKK2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CAMKK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-82 amino acids from the N-terminal region of human CAMKK2.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
52-82
Sequence Length
556
Applicable Applications for anti-CAMKK2 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with CAMKK2 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with CAMKK2 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
WB (Western Blot)
(Western blot analysis of CAMKK2 (arrow) using rabbit polyclonal CAMKK2 Antibody (N-term G67). 293 cell lysates (2 ug/lane) either nontransfected (c) or transiently transfected with the CAMKK2 gene (Lane 2) (Origene Technologies).)
WB (Western Blot)
(Western blot analysis of CAMKK2 (arrow) using rabbit polyclonal CAMKK2 Antibody (N-term G67). 293 cell lysates (2 ug/lane) either nontransfected (c) or transiently transfected with the CAMKK2 gene (Lane 2) (Origene Technologies).)
Related Product Information for anti-CAMKK2 antibody
CAMKK2 belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. CAMKK2 appears to be involved in hippocampal activation of CREB1.
Product Categories/Family for anti-CAMKK2 antibody
References
Hsu, L.S., et al., J. Biol. Chem. 276(33):31113-31123 (2001).
Hsu, L.S., et al., J. Biomed. Sci. 5(2):141-149 (1998).
Anderson, K.A., et al., J. Biol. Chem. 273(48):31880-31889 (1998).
Ishikawa, Y., et al., FEBS Lett. 550 (1-3), 57-63 (2003)
Hsu, L.S., et al., J. Biomed. Sci. 5(2):141-149 (1998).
Anderson, K.A., et al., J. Biol. Chem. 273(48):31880-31889 (1998).
Ishikawa, Y., et al., FEBS Lett. 550 (1-3), 57-63 (2003)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
64746
NCBI Official Full Name
calcium/calmodulin-dependent protein kinase kinase 2 isoform 1
NCBI Official Synonym Full Names
calcium/calmodulin-dependent protein kinase kinase 2, beta
NCBI Official Symbol
CAMKK2
NCBI Official Synonym Symbols
CAMKK; CAMKKB
NCBI Protein Information
calcium/calmodulin-dependent protein kinase kinase 2
UniProt Protein Name
Calcium/calmodulin-dependent protein kinase kinase 2
UniProt Gene Name
CAMKK2
UniProt Synonym Gene Names
CAMKKB; KIAA0787; CaM-KK 2; CaM-kinase kinase 2; CaMKK 2; CaM-KK beta; CaM-kinase kinase beta; CaMKK beta
UniProt Entry Name
KKCC2_HUMAN
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Product Notes
The CAMKK2 camkk2 (Catalog #AAA287163) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 52-82. The CAMKK2 Antibody (N-term G67) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CAMKK2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the CAMKK2 camkk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CAMKK2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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